Ohki Takao
Division of Vascular Surgery, Department of Surgery, Jikei University, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 2011 Jan;112(1):26-31.
We have utilized a custom-made branched stent graft (SG) in combination with a covered stent for the treatment of thoracoabdominal aneurysms (TAAAs) that were deemed to be inoperable due to co-morbid conditions or a hostile thorax/abdomen. During the last 3 years, 121 patients with TAAAs were treated at Jikei University Hospital. Those that were deemed to be good risk (n = 43) underwent traditional surgical repair. Those in whom the TAAA was considered inoperable (n = 50) were treated with a custom-made branched SG in combination with a covered stent, while those that were considered intermediate risk (n = 29) underwent debranching bypass surgery of the visceral branches followed by stent grafting using standard SGs without fenestrations. Although patients undergoing branched SG were older and had more ischemic heart disease and chronic obstructive pulmonary disease, the surgical mortality rate, paraplegia rate, mean aneurysm size, and operative time in the endovascular TAAA group were 5%, 2.6%, 6.5 cm, and 395 min, respectively, and those in the TAAA with branched SG group were 2%, 2%, 6.5 cm, and 366 min, respectively. Six cases in the endovascular group required secondary intervention, all of which were performed percutaneously. No TAAA rupture has been encountered. Our experience has therefore confirmed that branched SG repair is feasible and safe. Further investigations with more patients are warranted.
我们使用了一种定制的分支型覆膜支架(SG)与覆膜支架相结合,用于治疗因合并症或胸/腹部条件不佳而被认为无法手术的胸腹主动脉瘤(TAAA)。在过去3年中,东京慈惠会医科大学医院共治疗了121例TAAA患者。那些被认为手术风险低的患者(n = 43)接受了传统手术修复。那些被认为无法进行TAAA手术的患者(n = 50)采用定制的分支型SG与覆膜支架相结合进行治疗,而那些被认为手术风险中等的患者(n = 29)则先进行内脏分支去分支旁路手术,然后使用无开窗的标准SG进行支架植入。尽管接受分支型SG治疗 的患者年龄较大,且患有更多的缺血性心脏病和慢性阻塞性肺疾病,但血管内TAAA组的手术死亡率、截瘫率、平均动脉瘤大小和手术时间分别为5%、2.6%、6.5 cm和395分钟,而分支型SG治疗TAAA组的分别为2%、2%、6.5 cm和366分钟。血管内组有6例患者需要二次干预,均通过经皮方式进行。未发生TAAA破裂。因此,我们的经验证实了分支型SG修复是可行且安全的。有必要对更多患者进行进一步研究。