儿童注意缺陷多动障碍患者静脉导管插入时唾液皮质醇反应性。
Salivary cortisol responsivity to an intravenous catheter insertion in children with attention-deficit/hyperactivity disorder.
机构信息
College of Nursing, University of Iowa, Iowa City, IA 52242, USA.
出版信息
J Pediatr Psychol. 2011 Sep;36(8):902-10. doi: 10.1093/jpepsy/jsr012. Epub 2011 Mar 9.
Abstract
OBJECTIVE
To compare salivary cortisol baseline levels and responsivity as well as behavioral distress to intravenous (IV) catheter insertions in 4- to 10-year-old children with (n = 29) and without (n = 339) attention-deficit/hyperactivity disorder (ADHD).
METHODS
This is a secondary data analysis from a sample of 542 children who participated in a multisite study on distraction. Data included were demographic variables, Pediatric Behavior Scale-30, Observational Scale of Behavioral Distress-Revised, and four salivary cortisol samples.
RESULTS
Home samples from the ADHD group revealed nonsignificant but higher cortisol levels than the non-ADHD group. However, on the clinic day, the ADHD group had significantly lower cortisol levels before (0.184 vs. 0.261, p = .040) and 20-30 min after IV insertion (0.186 vs. 0.299, p = .014) compared with the non-ADHD group.
CONCLUSIONS
Cortisol levels in children with and without ADHD differ in response to the stress of an IV insertion.
摘要
目的
比较 4 至 10 岁儿童中患有（n=29）和不患有（n=339）注意缺陷多动障碍（ADHD）的儿童静脉（IV）导管插入术时唾液皮质醇基线水平和反应性以及行为困扰。
方法
这是对 542 名儿童参加分心多中心研究的样本进行的二次数据分析。数据包括人口统计学变量、儿科行为量表-30、行为困扰观察量表修订版和四个唾液皮质醇样本。
结果
ADHD 组的家庭样本显示皮质醇水平虽无显著差异但高于非 ADHD 组。然而，在就诊日，ADHD 组在 IV 插入前（0.184 与 0.261，p=0.040）和 20-30 分钟后（0.186 与 0.299，p=0.014）的皮质醇水平显著低于非 ADHD 组。
结论
ADHD 儿童和非 ADHD 儿童对 IV 插入应激的皮质醇水平反应不同。
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