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Nalidixic acid-resistant strains of Salmonella showing decreased susceptibility to fluoroquinolones in the midwestern region of the Republic of Ireland due to mutations in the gyrA gene.

作者信息

Ryan Michael P, Dillon Colm, Adley Catherine C

出版信息

J Clin Microbiol. 2011 May;49(5):2077-9. doi: 10.1128/JCM.02574-10. Epub 2011 Mar 9.

DOI:10.1128/JCM.02574-10
PMID:21389151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3122662/
Abstract
摘要

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Nalidixic acid-resistant strains of Salmonella showing decreased susceptibility to fluoroquinolones in the midwestern region of the Republic of Ireland due to mutations in the gyrA gene.由于gyrA基因突变，爱尔兰共和国中西部地区出现对萘啶酸耐药的沙门氏菌菌株，这些菌株对氟喹诺酮类药物的敏感性降低。
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本文引用的文献

1
Suitable disk antimicrobial susceptibility breakpoints defining Salmonella enterica serovar Typhi isolates with reduced susceptibility to fluoroquinolones.适合的药敏折点定义对氟喹诺酮类药物敏感性降低的肠炎沙门氏菌 Typhi 分离株。
Antimicrob Agents Chemother. 2010 Dec;54(12):5201-8. doi: 10.1128/AAC.00963-10. Epub 2010 Sep 13.
2
Ten years experience of Salmonella infections in Cambridge, UK.英国剑桥地区沙门氏菌感染十年经验。
J Infect. 2010 Jan;60(1):21-5. doi: 10.1016/j.jinf.2009.09.016. Epub 2009 Oct 9.
3
Antimicrobial resistance in typhoidal and nontyphoidal salmonellae.伤寒和非伤寒沙门氏菌中的抗菌素耐药性。
Curr Opin Infect Dis. 2008 Oct;21(5):531-8. doi: 10.1097/QCO.0b013e32830f453a.
4
Ciprofloxacin resistance in non-typhoidal Salmonella serotypes in Scotland, 1993-2003.1993 - 2003年苏格兰非伤寒沙门氏菌血清型对环丙沙星的耐药性
J Antimicrob Chemother. 2005 Jul;56(1):110-4. doi: 10.1093/jac/dki164. Epub 2005 May 24.
5
Clonal expansion may account for high levels of quinolone resistance in Salmonella enterica serovar enteritidis.克隆扩增可能是肠炎沙门氏菌肠炎血清型对喹诺酮类药物产生高耐药性的原因。
Appl Environ Microbiol. 2005 May;71(5):2587-91. doi: 10.1128/AEM.71.5.2587-2591.2005.
6
Increasing prevalence of quinolone resistance in human nontyphoid Salmonella enterica isolates obtained in Spain from 1981 to 2003.1981年至2003年在西班牙获得的人类非伤寒型肠炎沙门氏菌分离株中喹诺酮耐药性患病率不断上升。
Antimicrob Agents Chemother. 2004 Oct;48(10):3789-93. doi: 10.1128/AAC.48.10.3789-3793.2004.
7
Reevaluating fluoroquinolone breakpoints for Salmonella enterica serotype Typhi and for non-Typhi salmonellae.重新评估肠炎沙门氏菌伤寒血清型和非伤寒沙门氏菌的氟喹诺酮类药物断点。
Clin Infect Dis. 2003 Jul 1;37(1):75-81. doi: 10.1086/375602. Epub 2003 Jun 20.
8
Nalidixic acid-resistant strains of Salmonella showing decreased susceptibility to fluoroquinolones in the mid-west region of the Republic of Ireland.在爱尔兰共和国中西部地区，对萘啶酸耐药的沙门氏菌菌株对氟喹诺酮类药物的敏感性降低。
J Antimicrob Chemother. 2003 Apr;51(4):1047-9. doi: 10.1093/jac/dkg159. Epub 2003 Feb 25.
9
Is it time to change fluoroquinolone breakpoints for Salmonella spp.?是时候改变沙门氏菌属的氟喹诺酮类药物断点了吗？
Antimicrob Agents Chemother. 2003 Feb;47(2):827-9. doi: 10.1128/AAC.47.2.827-829.2003.
10
Comparative studies of mutations in animal isolates and experimental in vitro- and in vivo-selected mutants of Salmonella spp. suggest a counterselection of highly fluoroquinolone-resistant strains in the field.对动物分离株以及沙门氏菌属体外和体内实验选择突变株中的突变进行的比较研究表明，在实际环境中存在对高氟喹诺酮抗性菌株的反选择作用。
Antimicrob Agents Chemother. 1999 Sep;43(9):2131-7. doi: 10.1128/AAC.43.9.2131.