Einstein Institute for Heart and Vascular Health, Albert Einstein Medical Center, and Jefferson Medical College, Philadelphia, PA, USA.
Rev Cardiovasc Med. 2010 Fall;11(4):218-27. doi: 10.3909/ricm0551.
Infiltrative diseases targeting the cardiovascular system are a subgroup of restrictive cardiomyopathies. An early diagnosis is critical in initiating therapy to mitigate the deleterious effects of the pathologic process underlying these forms of cardiomyopathies. Infiltrative cardiac disease is rare and therefore often underdiagnosed. This review outlines the prevalence of 3 of the most common forms of restrictive cardiomyopathy: sarcoidosis, hemochromatosis, and amyloidosis. Infiltrative cardiomyopathy can have a variable prognosis depending on its etiology. It is a progressive disorder that, if left untreated, can lead to early mortality. A summary of the pathology, diagnosis, disease course, and therapy is provided, along with the utility of noninvasive testing as a means of diagnosis.
累及心血管系统的浸润性疾病是限制型心肌病的一个亚组。早期诊断对于启动治疗以减轻这些形式的心肌病潜在病理过程的有害影响至关重要。浸润性心脏疾病较为罕见，因此常常被漏诊。本综述概述了 3 种最常见的限制型心肌病的患病率：结节病、血色病和淀粉样变性。浸润性心肌病的预后因其病因而异。它是一种进行性疾病，如果不治疗，可导致早期死亡。提供了病理学、诊断、病程和治疗的总结，以及非侵入性检查作为诊断手段的效用。
