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冠状动脉支架置入术治疗药物抵抗性血管痉挛患者。

Coronary stenting in patients with medically resistant vasospasm.

机构信息

Division of Cardiology, The Southern Arizona VA Health Care System, and University of Arizona Sarver Heart Center, Tucson, AZ, USA.

出版信息

Rev Cardiovasc Med. 2010 Fall;11(4):264-70. doi: 10.3909/ricm0545.

Abstract

Formally described by Prinzmetal and colleagues in 1959, variant angina represents a syndrome of resting angina that results from severe coronary artery vasospasm associated with ST elevation. The majority of patients respond to nitrates or calcium channel blockers. However, medical treatment-resistant vasospasm can occur in up to 20% of cases, thus requiring further interventions. We present a rare instance of coronary vasospasm associated with complete heart block resistant to medical therapy that was successfully treated with stenting. This case example is followed by a detailed review of the literature with regard to percutaneous or surgical coronary revascularization of patients with medically resistant vasospasm.

摘要

1959 年,由 Prinzmetal 及其同事正式描述,变异性心绞痛是一种静息性心绞痛综合征,由严重的冠状动脉痉挛引起,伴有 ST 段抬高。大多数患者对硝酸酯类或钙通道阻滞剂有反应。然而,高达 20%的病例可能出现药物治疗抵抗性的血管痉挛,因此需要进一步的干预措施。我们报告了一例罕见的与完全性心脏阻滞相关的冠状动脉痉挛,该病例对药物治疗有抵抗,经支架置入治疗后成功缓解。随后对文献进行了详细回顾,包括药物治疗抵抗性血管痉挛患者的经皮或手术冠状动脉血运重建。

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