Santini S, Barbera P, Modena M, Schiavon R, Bonato M
Unit of Orthopedics and Traumatology, "San Bortolo" Hospital, Vicenza, Italy.
Minerva Chir. 2011 Feb;66(1):63-72.
To evaluate the use of equine-derived bone grafts in the treatment of bone loss in a heterogeneous clinical case series.
The study population was 48 patients (29 males and 19 females; mean age, 49 years; range, 9-84); the orthopedic defect site was located on the right side in 22 and on the left side in 26 cases. The graft material was antigen-free equine-derived collagen bone cleaned with an enzymatic treatment.
Clinical and radiographic healing times were virtually similar; graft osseointegration needed from two to three months longer to heal.
The outcome after grafting with an equine-derived bone substitute was satisfactory. Further study is needed to demonstrate its statistically significant effectiveness in the treatment of orthopedic defects like those in this series.
在一个异质性临床病例系列中评估马源骨移植材料在治疗骨缺损中的应用。
研究对象为48例患者（29例男性和19例女性；平均年龄49岁；范围9 - 84岁）；骨科缺损部位右侧22例，左侧26例。移植材料为经酶处理清洁的无抗原马源胶原骨。
临床和影像学愈合时间基本相似；移植骨骨整合愈合需要两到三个月更长时间。
使用马源骨替代物移植后的结果令人满意。需要进一步研究以证明其在治疗此类系列骨科缺损中具有统计学意义的有效性。
