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采用马源骨移植进行颅下Le Fort III型前移矫正综合征性面中部发育不全:1例报告

Subcranial Le Fort III Advancement with Equine-Derived Bone Grafts to Correct Syndromic Midfacial Hypoplasia: A Case Report.

作者信息

Mattioli Beniamino, Iacoviello Paolo, Aldiano Carola, Verrina Giuseppe

机构信息

1Maxillo-Facial Surgery Department, E.O. Ospedali Galliera, Via Mura delle Cappuccine 14, 16128 Genoa, Italy.

Via Belvedere 3 A, 16011 Arenzano, Genoa, Italy.

出版信息

J Maxillofac Oral Surg. 2018 Sep;17(3):296-300. doi: 10.1007/s12663-017-1058-z. Epub 2017 Nov 28.

DOI:10.1007/s12663-017-1058-z
PMID:30034147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6028328/
Abstract

Patients with hypoplasia of the midface normally present a flattening of their facial profile due to insufficient development of the nose and maxilla. Treatment aimed to restore function and an aesthetic appearance calls for a Le Fort III osteotomy and the advancement of the midfacial segment either through distraction or interposition of autogenous bone blocks. However, drawbacks in using autogenous bone suggest that use of alternative graft material may be advisable. The present report describes a Le Fort III advancement using two enzyme-treated equine cancellous bone blocks to correct syndromic midfacial hypoplasia in a 22-year-old patient. A 12-mm surgical advancement was achieved, improving the patient's facial profile. At the 28-month follow-up, the midface advanced position was stable. Equine bone blocks could be a valid alternative to autogenous bone in Le Fort III midface advancement.

摘要

面中部发育不全的患者通常由于鼻子和上颌骨发育不足而呈现面部轮廓扁平。旨在恢复功能和美观外观的治疗需要进行Le Fort III截骨术,并通过牵引或自体骨块植入来推进面中部节段。然而,使用自体骨的缺点表明,使用替代移植材料可能是可取的。本报告描述了使用两块经酶处理的马松质骨块进行Le Fort III推进术,以矫正一名22岁患者的综合征性面中部发育不全。实现了12毫米的手术推进,改善了患者的面部轮廓。在28个月的随访中,面中部的推进位置稳定。在Le Fort III面中部推进术中,马骨块可能是自体骨的有效替代物。

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本文引用的文献

1
LeFort I Osteotomy.LeFort I 截骨术。
Semin Plast Surg. 2013 Aug;27(3):149-54. doi: 10.1055/s-0033-1357112.
2
Le Fort IV + I distraction osteogenesis using an internal device for syndromic craniosynostosis.使用内部装置进行综合征性颅缝早闭的Le Fort IV + I型牵张成骨术。
J Oral Maxillofac Surg. 2014 Apr;72(4):788-95. doi: 10.1016/j.joms.2013.09.041. Epub 2013 Oct 10.
3
Le Fort III distraction osteogenesis versus conventional Le Fort III osteotomy in correction of syndromic midfacial hypoplasia: a systematic review.勒福Ⅲ型牵张成骨术与传统勒福Ⅲ型截骨术矫治综合征性面中部发育不全的系统评价
J Oral Maxillofac Surg. 2014 May;72(5):959-72. doi: 10.1016/j.joms.2013.09.039. Epub 2013 Oct 9.
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Calcium phosphate cements for bone substitution: chemistry, handling and mechanical properties.用于骨替代的磷酸钙骨水泥:化学、操作及力学性能
Acta Biomater. 2014 Mar;10(3):1035-49. doi: 10.1016/j.actbio.2013.11.001. Epub 2013 Nov 11.
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Site selection and pain outcome after autologous bone graft harvest.自体骨移植采集后的部位选择与疼痛结局。
Foot Ankle Int. 2014 Feb;35(2):104-7. doi: 10.1177/1071100713511434. Epub 2013 Nov 13.
6
Monobloc minus Le Fort II for single-stage treatment of the Apert phenotype.整块式减Le Fort II型手术用于Apert综合征的单阶段治疗。
J Craniofac Surg. 2013 Mar;24(2):596-8. doi: 10.1097/SCS.0b013e318280233d.
7
Case of severe bone atrophy of the posterior maxilla rehabilitated with blocks of equine origin bone: histological results.严重上颌骨后部萎缩病例的修复:采用马源性块状骨:组织学结果。
Implant Dent. 2013 Feb;22(1):8-15. doi: 10.1097/ID.0b013e3182777239.
8
Current trends and future perspectives of bone substitute materials - from space holders to innovative biomaterials.当前骨替代材料的趋势和未来展望——从空间占位到创新生物材料。
J Craniomaxillofac Surg. 2012 Dec;40(8):706-18. doi: 10.1016/j.jcms.2012.01.002. Epub 2012 Jan 31.
9
Bone allografts: a review of safety and efficacy.骨移植:安全性与有效性综述
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Sinus lift with autologous bone alone or in addition to equine bone: an immunohistochemical study in man.单纯使用自体骨或联合使用马骨进行上颌窦提升:一项针对人类的免疫组织化学研究。
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