Golan A, Ron-el R, Herman A, Weinraub Z, Soffer Y, Caspi E
Department of Obstetrics and Gynaecology, Assaf Harofe Medical Centre, Zerifin, Israel.
Hum Reprod. 1990 Jan;5(1):123-4. doi: 10.1093/oxfordjournals.humrep.a137031.
Early follicular use of long-acting analogues of gonadotrophin releasing hormone (GnRH) in IVF programmes has caused some concern with respect to its teratogenic potential. In the case reported here, an injection of DTRP6 GnRH microcapsules was given in the 5th week of a spontaneous unsuspected pregnancy. No deleterious effect or teratogenesis of the embryo could be demonstrated at birth or 18 months later.
在体外受精（IVF）程序中，在卵泡早期使用促性腺激素释放激素（GnRH）长效类似物引发了对其致畸潜力的一些担忧。在本文报道的病例中，在一次未被怀疑的自然妊娠第5周注射了DTRP6 GnRH微胶囊。在出生时或18个月后均未发现胚胎有有害影响或致畸情况。
