Brown M M, Butler P, Gibbs J, Swash M, Waterston J
Department of Neurology, London Hospital, Whitechapel, United Kingdom.
J Neurol Neurosurg Psychiatry. 1990 Mar;53(3):238-43. doi: 10.1136/jnnp.53.3.238.
Percutaneous transluminal balloon angioplasty was attempted in seven patients with internal carotid artery stenosis, including one patient who had two procedures. All had recurrent, carotid territory, neurological symptoms considered haemodynamic in origin. Six had occlusion of the contralateral internal carotid artery. Cerebral blood flow studies confirmed diminished cerebrovascular reserve in six patients studied. In five patients (six procedures) angioplasty of the stenosed internal carotid artery was carried out successfully. With two patients technical difficulty in crossing the stenosis prevented angioplasty and in one patient with bilateral stenosis the procedure was not attempted on the second side because of the severity of the stenosis. In two patients transient aphasia developed during cannulation of the carotid artery and in another a transient monoparesis developed during the procedure. Both these haemodynamic complications recovered within ten minutes. No other complications occurred. Our experience suggests that balloon angioplasty is technically feasible in the management of stenotic carotid disease associated with haemodynamic stroke. It is a technically simple procedure requiring only a brief admission to hospital. However, its general application to patients with thromboembolic carotid-territory stroke will depend on the risk/benefit ratio compared to carotid endarterectomy or to conventional medical treatment.
对7例颈内动脉狭窄患者尝试进行经皮腔内球囊血管成形术,其中1例患者接受了两次手术。所有患者均有反复发作的、颈动脉供血区的、被认为起源于血流动力学的神经症状。6例患者对侧颈内动脉闭塞。脑血流研究证实,在接受研究的6例患者中脑血管储备减少。5例患者(6次手术)成功地对狭窄的颈内动脉进行了血管成形术。2例患者因技术上难以穿过狭窄部位而未能进行血管成形术,1例双侧狭窄患者因狭窄严重而未对另一侧进行该手术。2例患者在颈动脉插管过程中出现短暂性失语,另1例患者在手术过程中出现短暂性单瘫。这两种血流动力学并发症均在10分钟内恢复。未发生其他并发症。我们的经验表明,球囊血管成形术在治疗与血流动力学性卒中相关的颈动脉狭窄疾病方面在技术上是可行的。这是一种技术上简单的手术,只需要短暂住院。然而,与颈动脉内膜切除术或传统药物治疗相比,其在血栓栓塞性颈动脉供血区卒中患者中的广泛应用将取决于风险/效益比。