微波辅助非对映选择性多组分反应构建二苯并[c,e]氮杂卓酮：合成与生物评价。
A microwave-assisted diastereoselective multicomponent reaction to access dibenzo[c,e]azepinones: synthesis and biological evaluation.
机构信息
Laboratory for Organic & Microwave-Assisted Chemistry, Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.
出版信息
J Org Chem. 2011 Apr 15;76(8):2828-39. doi: 10.1021/jo200251q. Epub 2011 Mar 22.
PMID:21391618
Abstract
An unprecedented microwave-assisted multicomponent strategy has been elaborated for the fast, efficient, and diastereoselective generation of the dibenzo[c,e]azepinone scaffold. The generated compounds were evaluated for their bioactivity.
摘要
一种前所未有的微波辅助多组分策略被精心设计用于快速、高效和立体选择性地生成二苯并[c,e]氮杂卓骨架。所生成的化合物进行了生物活性评估。
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