Antibacterial activity of some bryophytes used traditionally for the treatment of burn infections.

CONTEXT

Plagiochasma appendiculatum L. & L. (Aytoniaceae), Conocephalum conicum (L.) Necker (Conocephalaceae), Bryum argenteum Hedw. (Bryaceae), and Mnium marginatum (With.) P. Beauv. (Mniaceae) are bryophytes (liverworts and mosses) used by traditional healers for the treatment of burn, cuts, wounds, and skin disorders.

OBJECTIVE

This study evaluated the antibacterial activity of four bryophytes against some common bacteria responsible for burn infections.

MATERIALS AND METHODS

Different fractions of bryophytes were screened using the disc diffusion (qualitative) and broth microdilution (quantitative) methods, according to the guidelines of the National Committee for Clinical and Laboratory Standards.

RESULTS AND DISCUSSION

Chloroform fractions of liverworts were more active against Gram negative strains while butanol fractions of mosses had significant activity against Gram positive bacteria. Staphylococcus aureus was the most sensitive strain of those tested with the butanol fraction of M. marginatum (moss), with the strongest inhibition zone of 102.92% and minimum inhibitory concentration of 30 μg mL(-1).

CONCLUSION

Our findings support the use of the bryophytes in traditional medicine for burn infections because of their significant antibacterial activity.