Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, Lucknow, India.
Pharm Biol. 2011 May;49(5):526-30. doi: 10.3109/13880209.2010.523007. Epub 2011 Mar 11.
Plagiochasma appendiculatum L. & L. (Aytoniaceae), Conocephalum conicum (L.) Necker (Conocephalaceae), Bryum argenteum Hedw. (Bryaceae), and Mnium marginatum (With.) P. Beauv. (Mniaceae) are bryophytes (liverworts and mosses) used by traditional healers for the treatment of burn, cuts, wounds, and skin disorders.
This study evaluated the antibacterial activity of four bryophytes against some common bacteria responsible for burn infections.
Different fractions of bryophytes were screened using the disc diffusion (qualitative) and broth microdilution (quantitative) methods, according to the guidelines of the National Committee for Clinical and Laboratory Standards.
Chloroform fractions of liverworts were more active against Gram negative strains while butanol fractions of mosses had significant activity against Gram positive bacteria. Staphylococcus aureus was the most sensitive strain of those tested with the butanol fraction of M. marginatum (moss), with the strongest inhibition zone of 102.92% and minimum inhibitory concentration of 30 μg mL(-1).
Our findings support the use of the bryophytes in traditional medicine for burn infections because of their significant antibacterial activity.
胎生狗脊蕨（水龙骨目水龙骨科）、头状穗莎草（莎草目莎草科）、银叶真藓（真藓目真藓科）和边缘金发藓（金发藓目金发藓科）是被传统医者用于治疗烧伤、割伤、创伤和皮肤疾病的苔藓植物（包括苔类和藓类）。
本研究评估了四种苔藓植物对一些常见烧伤感染细菌的抗菌活性。
根据国家临床和实验室标准委员会的指导，使用圆盘扩散（定性）和肉汤微量稀释（定量）方法对苔藓植物的不同部位进行筛选。
苔类植物的氯仿部位对革兰氏阴性菌的活性更强，而藓类植物的正丁醇部位对革兰氏阳性菌具有显著的活性。金黄色葡萄球菌是测试菌株中最敏感的菌株，与边缘金发藓（藓类）的正丁醇部位相比，其抑制带最强，为 102.92%，最小抑菌浓度为 30μg/mL。
我们的研究结果支持了苔藓植物在传统医学中用于烧伤感染的应用，因为它们具有显著的抗菌活性。
