Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel HaShomer, Israel.
J Perinat Med. 2011 May;39(3):305-9. doi: 10.1515/jpm.2011.009. Epub 2011 Mar 11.
To evaluate the correlation between sonographic measurements of nuchal translucency (NT) and neonatal birth weight in non-diabetic population.
A retrospective analysis was performed on all singleton term pregnancies delivered at our hospital between 2004 and 2008. Data collected included maternal age, parity, NT measurement, results of glucose challenge test, birth weight, gestational age at delivery, and fetal gender.
The study population comprised of 1649 patients. The mean NT was 1.3 ± 0.5 mm. Male fetuses had a significantly thicker NT (1.3 ± 0.5 vs. 1.2 ± 0.4; P<0.001). NT significantly correlated to birth weight (P=0.002). This correlation was independent of neonatal gender. The median NT in the large for gestational age (LGA) neonates was significantly higher than in the non-LGA neonates (1.4 mm vs. 1.2 mm, P=0.001). Equations for the predicted probability for delivering LGA neonates were derived using either NT alone or in combination with parity. An increase in 0.1 mm in the NT has the odd ratio of 1.042 for delivering an LGA neonate (P=0.02).
NT correlated with LGA neonates in term non-diabetic patients. This correlation was independent of the neonatal gender. The predictive clinical impact of NT was limited to LGA neonates.
评估非糖尿病人群颈项透明层（NT）超声测量值与新生儿出生体重之间的相关性。
对 2004 年至 2008 年在我院分娩的所有单胎足月妊娠进行回顾性分析。收集的数据包括母亲年龄、产次、NT 测量值、葡萄糖挑战试验结果、出生体重、分娩时的胎龄和胎儿性别。
研究人群包括 1649 例患者。NT 的平均值为 1.3 ± 0.5mm。男性胎儿的 NT 明显更厚（1.3 ± 0.5 比 1.2 ± 0.4；P<0.001）。NT 与出生体重显著相关（P=0.002）。这种相关性与新生儿性别无关。巨大儿（LGA）新生儿的中位数 NT 明显高于非 LGA 新生儿（1.4mm 比 1.2mm，P=0.001）。使用 NT 或与产次联合使用，得出预测 LGA 新生儿的概率方程。NT 增加 0.1mm 时，LGA 新生儿的比值比为 1.042（P=0.02）。
NT 与非糖尿病足月患者的 LGA 新生儿相关。这种相关性与新生儿性别无关。NT 的预测临床影响仅限于 LGA 新生儿。
