Cros D, Comp P C, Beltran G, Gum G
Department of Psychiatry, Tulane University School of Medicine, New Orleans, Louisiana.
Stroke. 1990 Apr;21(4):633-6. doi: 10.1161/01.str.21.4.633.
A 30-year-old man presented with sagittal sinus thrombosis. He had a history of multiple thrombotic events since adolescence, and his father had had a similar history. Laboratory studies revealed the complete absence of free protein S in his plasma. Protein S deficiency, an autosomal dominant disorder, is an identifiable cause of cerebral thrombosis. The literature and our experience with this case suggest that long-term anticoagulant therapy may prevent thrombotic episodes in patients with this disorder.
一名30岁男性因矢状窦血栓形成前来就诊。他自青少年期起就有多次血栓形成事件的病史，其父亲也有类似病史。实验室检查显示他的血浆中完全缺乏游离蛋白S。蛋白S缺乏是一种常染色体显性疾病，是一种可明确的脑血栓形成病因。文献及我们对该病例的经验表明，长期抗凝治疗可能预防患有这种疾病的患者发生血栓形成事件。
