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马的镁紊乱

Magnesium disorders in horses.

作者信息

Stewart Allison J

机构信息

Department of Clinical Science, John Thomas Vaughan Large Animal Teaching Hospital, College of Veterinary Medicine, Auburn University, 1500 Wire Road, Auburn, AL 36849, USA.

出版信息

Vet Clin North Am Equine Pract. 2011 Apr;27(1):149-63. doi: 10.1016/j.cveq.2010.12.009.

DOI:10.1016/j.cveq.2010.12.009
PMID:21392659
Abstract

Magnesium (Mg) is an essential macroelement that is required for cellular energy-dependent reactions involving adenosine triphosphate and for the regulation of calcium channel function. Subclinical hypomagnesemia is common in critically ill humans and animals and increases the severity of the systemic inflammatory response syndrome; worsens the systemic response to endotoxins; and can lead to ileus, cardiac arrhythmias, refractory hypokalemia, and hypocalcemia. This article discusses the clinical signs, consequences, and treatment of hypomagnesemia in horses and describes the association of Mg and endotoxemia, insulin resistance, and brain injury.

摘要

镁(Mg)是一种必需的宏量元素,参与涉及三磷酸腺苷的细胞能量依赖性反应以及钙通道功能的调节。亚临床低镁血症在重症人类和动物中很常见,会增加全身炎症反应综合征的严重程度;加重对内毒素的全身反应;并可导致肠梗阻、心律失常、难治性低钾血症和低钙血症。本文讨论了马低镁血症的临床症状、后果和治疗方法,并描述了镁与内毒素血症、胰岛素抵抗和脑损伤之间的关联。

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1
Magnesium disorders in horses.马的镁紊乱
Vet Clin North Am Equine Pract. 2011 Apr;27(1):149-63. doi: 10.1016/j.cveq.2010.12.009.
2
Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function.原发性低镁血症中低钙血症的发病机制:终末器官对甲状旁腺激素反应正常,甲状旁腺功能受损。
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Alterations in serum parathyroid hormone and electrolyte concentrations and urinary excretion of electrolytes in horses with induced endotoxemia.内毒素血症诱导马匹血清甲状旁腺激素和电解质浓度以及电解质尿排泄的变化。
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The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows.奶牛生产瘫痪和亚临床低钙血症的监测、预防与治疗
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Parathyroid function during chronic magnesium deficiency.慢性镁缺乏时的甲状旁腺功能
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Hypomagnesemia in hospitalized patients receiving nutritional support.接受营养支持的住院患者中的低镁血症。
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Primary hypomagnesemia with secondary hypocalcemia. Report of a case and review of the world literature.原发性低镁血症伴继发性低钙血症。1例报告并复习世界文献。
Magnesium. 1985;4(2-3):153-64.
8
Prevalence and prognostic importance of hypomagnesemia and hypocalcemia in horses that have colic surgery.患有腹痛症接受手术的马匹低镁血症和低钙血症的患病率及预后重要性
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Parathyroid hormone secretion and responsiveness to parathyroid hormone in primary hypomagnesemia.原发性低镁血症中甲状旁腺激素的分泌及对甲状旁腺激素的反应性
Isr J Med Sci. 1983 Apr;19(4):345-8.
10
Magnesium replacement therapy.镁替代疗法。
Am Fam Physician. 1990 Jul;42(1):173-6.

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