宫腔镜子宫中隔切除术治疗子宫中隔伴不明原因不孕患者。
Hysteroscopic metroplasty in patients with a uterine septum and otherwise unexplained infertility.
机构信息
Department of Reproductive Endocrinology, Zekai Tahir Burak Woman's Health Education and Research Hospital, Ankara, Turkey.
出版信息
Int J Gynaecol Obstet. 2011 May;113(2):128-30. doi: 10.1016/j.ijgo.2010.11.023. Epub 2011 Mar 9.
OBJECTIVE
To evaluate the reproductive outcomes of patients with a uterine septum and otherwise unexplained infertility who underwent hysteroscopic metroplasty, and to compare them with those of patients with the same diagnosis who did not have hysteroscopic metroplasty.
METHODS
The present retrospective study included 127 patients with diagnosis of a uterine septum and otherwise unexplained infertility. The reproductive outcomes of 102 patients who underwent hysteroscopic metroplasty (group 1) and 25 patients who rejected the operation (group 2) were compared.
RESULTS
Of the 102 patients who underwent hysteroscopic metroplasty, 44 (43.1%) were able to achieve pregnancy, as compared with 5 (20%) of the 25 patients who did not undergo the operation (P=0.03). The abortion rate was 11.4% (5/44) in group 1, compared with 60% (3/5) in group 2 (P=0.02). The live birth rate was 35.3% (36/102) in group 1, as compared with 8% (2/25) in group 2 (P=0.008).
CONCLUSIONS
The results indicate that hysteroscopic metroplasty improves reproductive outcome for patients with a uterine septum and otherwise unexplained infertility.
目的
评估因子宫中隔和其他不明原因不孕而行宫腔镜子宫中隔切除术患者的生殖结局，并与未行宫腔镜子宫中隔切除术的相同诊断患者的生殖结局进行比较。
方法
本回顾性研究纳入了 127 例诊断为子宫中隔和其他不明原因不孕的患者。比较了 102 例行宫腔镜子宫中隔切除术（第 1 组）和 25 例拒绝手术的患者（第 2 组）的生殖结局。
结果
在 102 例行宫腔镜子宫中隔切除术的患者中，44 例（43.1%）能够怀孕，而未行手术的 25 例患者中，有 5 例（20%）能够怀孕（P=0.03）。第 1 组的流产率为 11.4%（5/44），而第 2 组为 60%（3/5）（P=0.02）。第 1 组的活产率为 35.3%（36/102），而第 2 组为 8%（2/25）（P=0.008）。
结论
结果表明，宫腔镜子宫中隔切除术可改善因子宫中隔和其他不明原因不孕而行手术的患者的生殖结局。
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