窄带成像内镜检测出鼻咽癌。
Nasopharyngeal carcinoma detected by narrow-band imaging endoscopy.
机构信息
Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital at Chiayi, Graduate Institute of Clinical Medical Sciences, Chang Gung University, College of Medicine, No. 6 West Section, Chia-Pu Road, Pu-Tzu City, Chiayi County 613, Taiwan.
出版信息
Oral Oncol. 2011 Aug;47(8):736-41. doi: 10.1016/j.oraloncology.2011.02.012. Epub 2011 Mar 9.
The aim of the study was to investigate the novel endoscopic findings in nasopharyngeal carcinoma (NPC) under narrow-band imaging (NBI) and to determine the reliability of screening NPC by NBI. A total of 79 adults underwent nasopharyngeal biopsy. We proposed five distinctly different findings that need to be examined by NBI: Type I: brownish spots, Type II: irregular microvascular pattern (IMVP), Type III: light crests, Type IV: side-difference, Type V: presence of either IMVP or side-difference, of which last three (Type III-V) were a new concept. The results of NPC diagnosis by detecting NBI Type V pattern, the false positive, false negative, sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 6.7%, 2.9%, 97.1%, 93.3%, 91.7%, 97.7%, and 94.9%, respectively. On the other hand, there was a higher prevalence of Type I and IV patterns in T1 category NPC. The nasopharyngeal endoscopy coupled with NBI was able to provide a rapid, convenient, and highly reliable screening for high-risk populations.
本研究旨在探讨窄带成像（NBI）下鼻咽癌（NPC）的新内镜表现，并确定 NBI 筛查 NPC 的可靠性。共有 79 名成年人接受了鼻咽活检。我们提出了五种需要通过 NBI 检查的明显不同的发现：I 型：棕色斑点，II 型：不规则微血管模式（IMVP），III 型：淡嵴，IV 型：侧差异，V 型：存在 IMVP 或侧差异，其中后三种（III-V 型）是新概念。通过检测 NBI V 型模式诊断 NPC 的结果为假阳性率 6.7%，假阴性率 2.9%，灵敏度 97.1%，特异性 93.3%，阳性预测值 97.7%，阴性预测值 94.9%，准确性 94.9%。另一方面，T1 期 NPC 中 I 型和 IV 型模式更为常见。鼻咽内镜联合 NBI 能够为高危人群提供快速、方便、高度可靠的筛查。
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