Department of Neurology, Division of Epilepsy, Vanderbilt University Medical Center, Nashville, TN 37232-2551, USA.
Epileptic Disord. 2011 Mar;13(1):92-5. doi: 10.1684/epd.2011.0405.
We report the pattern of seizure propagation as detected by functional MRI (fMRI) in a 24-year-old man with frequent recurrent electrographic seizures. The EEG seizure onset was left occipital with later spread to the left hemisphere and, to a lesser extent, the right hemisphere. The fMRI showed initial increase in blood oxygen level-dependent (BOLD) signal in the left occipital pole. The increased signal then propagated to the right occipital-posterotemporal region, and subsequently, the right and left mesial temporal regions. fMRI can be an effective tool to study seizure onset localization and seizure propagation in patients with frequent recurrent seizures.
我们报告了一位 24 岁男性频繁出现脑电图癫痫发作时，功能磁共振成像（fMRI）检测到的癫痫发作传播模式。脑电图癫痫发作起始于左枕叶，随后传播到左半球，程度较轻时也传播到右半球。fMRI 显示左枕极血氧水平依赖（BOLD）信号最初增加。增加的信号随后传播到右枕叶-后颞区，随后传播到右侧和左侧内侧颞区。fMRI 可以成为研究频繁出现癫痫发作患者癫痫发作起始定位和传播的有效工具。
