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室性心动过速转复期间及之后的血浆心房利钠因子浓度

Concentrations of plasma atrial natriuretic factor during and after reversion of ventricular tachycardia.

作者信息

Twidale N, Oliver J R, Menadue M, Tonkin A M

机构信息

Department of Medicine, Flinders Medical Centre, Bedford Park, South Australia.

出版信息

Br Heart J. 1990 Mar;63(3):154-6. doi: 10.1136/hrt.63.3.154.

Abstract

Plasma concentrations of immunoreactive atrial natriuretic factor were considerably increased (mean 745 (376) pg/ml) in 15 patients during spontaneous ventricular tachycardia. There was no significant relation, however, between concentrations of plasma atrial natriuretic factor and systolic arterial blood pressure during tachycardia. Samples taken 30 minutes and 24 hours after reversion of ventricular tachycardia to sinus rhythm showed that, although plasma concentrations of atrial natriuretic factor had fallen significantly, they were still raised after 24 hours. Raised concentrations of atrial natriuretic factor during ventricular tachycardia did not seem to contribute significantly to the hypotension that is often associated with the arrhythmia.

摘要

15例患者在发生自发性室性心动过速时,血浆免疫反应性心房利钠因子浓度显著升高(平均745(376)pg/ml)。然而,心动过速期间血浆心房利钠因子浓度与收缩期动脉血压之间无显著相关性。室性心动过速转为窦性心律后30分钟和24小时采集的样本显示,尽管血浆心房利钠因子浓度已显著下降,但24小时后仍升高。室性心动过速期间心房利钠因子浓度升高似乎对常与该心律失常相关的低血压无显著影响。

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本文引用的文献

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SPECIFIC GRANULES IN ATRIAL MUSCLE CELLS.心房肌细胞中的特殊颗粒。
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Paroxysmal tachycardia with polyuria.阵发性心动过速伴多尿
Ann Intern Med. 1966 Sep;65(3):461-70. doi: 10.7326/0003-4819-65-3-461.
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Renal effects of human alpha-atrial natriuretic polypeptide.人α-心房利钠多肽的肾脏效应
N Engl J Med. 1985 May 30;312(22):1456-7. doi: 10.1056/NEJM198505303122213.

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