18至35岁年轻成年人的猝死、意外及自然死亡：一项临床病理研究

Sudden, unexpected and natural death in young adults of age between 18 and 35 years: a clinicopathological study.

作者信息

Chaturvedi Madhu, Satoskar Meera, Khare Manisha S, Kalgutkar Alka D

机构信息

Department of Pathology, LTM General Hospital and Municipal Medical College, Mumbai, India.

出版信息

Indian J Pathol Microbiol. 2011 Jan-Mar;54(1):47-50. doi: 10.4103/0377-4929.77323.

DOI:10.4103/0377-4929.77323

PMID:21393876

Abstract

CONTEXT

To identify various causes, risk factors, age and sex distribution associated with sudden and unexpected natural deaths (SUNDs) in young adults of age between 18 and 35 years.

MATERIALS AND METHODS

Retrospective analysis of autopsy reports and medical records of all SUNDs that occurred instantaneously or within 24 hours of onset of symptoms in young adults, between 2001 and 2009.

RESULT

Of the total 6453 deaths autopsied during 2001-2009, 64 (0.99%) were SUNDs in young adults, chiefly in males between 30 and 35 years of age. Non-cardiac causes significantly predominated (73.4%) over cardiac causes (7.8%). Most of the SUND cases were due to preventable causes, including infections (54.6% cases), cerebrovascular accidents (9.37%) and ischemic cardiac causes (6.25%). Sudden adult death syndrome (SADS) accounted for 18.75% deaths.

CONCLUSION

SUND in young adults is preventable. A meticulous post-mortem examination with special attention to the conduction system of heart and detailed toxicological analysis can pinpoint the cause of death in SADS.

摘要

背景

确定18至35岁年轻成年人中与突然意外自然死亡（SUNDs）相关的各种原因、风险因素、年龄和性别分布。

材料与方法

对2001年至2009年间年轻成年人中所有在症状发作后立即或24小时内发生的SUNDs的尸检报告和医疗记录进行回顾性分析。

结果

在2001 - 2009年期间进行尸检的6453例死亡病例中，64例（0.99%）为年轻成年人的SUNDs，主要为30至35岁的男性。非心脏原因（73.4%）显著多于心脏原因（7.8%）。大多数SUND病例是由可预防的原因引起的，包括感染（54.6%的病例）、脑血管意外（9.37%）和缺血性心脏原因（6.25%）。成人猝死综合征（SADS）占死亡病例的18.75%。