Arumugam Ganesan, Jacob S Mini, Anitha D, Rajappa Sivakumar Mampakkam
Department of Experimental Medicine, TN Dr. MGR Medical University, Chennai, Guindy, Tamil Nadu, India.
Indian J Pathol Microbiol. 2011 Jan-Mar;54(1):100-2. doi: 10.4103/0377-4929.77340.
To evaluate the serological profile of leptospirosis by microscopic agglutination test (MAT) and dark field microscopy (DFM) and to determine the serovar prevalence rate among patients with pyrexia of unknown origin.
A total of 3830 blood samples were received from different hospitals and laboratories in and around Chennai. They were screened for leptospirosis by MAT and direct observation of live Leptospira by DFM.
A total of 748 (19.5%) Leptospira positive cases were identified; among these, 36.76% were Leptospira australis, 30% were Leptospira canicola, 14.57% were Leptospira autumnalis, 12% were Leptospira icterohaemorrhagiae, 4.68% were Leptospira patoc and 1.87% were Leptospira grippotyposa. Patients were in the age group of 1-86 years, with a median age of 43.5 years. 50% positive cases were in the age group of 10-35 years. Majority of the Leptospira infected cases were males (62.98%) than females (37.02%).
Leptospirosis occurs in Chennai throughout the year although the number and positivity of cases increased during the monsoon season.
通过显微镜凝集试验（MAT）和暗视野显微镜检查（DFM）评估钩端螺旋体病的血清学特征，并确定不明原因发热患者中的血清型流行率。
从金奈及其周边地区的不同医院和实验室共采集了3830份血样。通过MAT和DFM直接观察活钩端螺旋体对血样进行钩端螺旋体病筛查。
共鉴定出748例（19.5%）钩端螺旋体阳性病例；其中，澳洲钩端螺旋体占36.76%，犬型钩端螺旋体占30%，秋季钩端螺旋体占14.57%，出血性黄疸钩端螺旋体占12%，波摩那群钩端螺旋体占4.68%，七日热钩端螺旋体占1.87%。患者年龄在1至86岁之间，中位年龄为43.5岁。50%的阳性病例年龄在10至35岁之间。钩端螺旋体感染病例中男性（62.98%）多于女性（37.02%）。
金奈全年均有钩端螺旋体病发生，尽管病例数和阳性率在季风季节有所增加。
