Department of Inorganic and Organic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, 500 05, Hradec Králové, Czech Republic.
Folia Microbiol (Praha). 2011 Jan;56(1):10-2. doi: 10.1007/s12223-011-0015-3. Epub 2011 Mar 11.
Benzaldehyde- and salicylaldehyde-S-benzylisothiosemicarbazones show a moderate to high in vitro activity against Mycobacterium tuberculosis, Mycobacterium avium and two strains of Mycobacterium kansasii. Benzaldehyde-S-4-bromobenzylisothiosemicarbazone and salicylaldehyde-S-4-chlorobenzylisothiosemicarbazone have the most promising antimycobacterial properties.
苯甲醛-和水杨醛-S-苄基异硫代氰酸脒显示出对结核分枝杆菌、鸟分枝杆菌和两种堪萨斯分枝杆菌菌株具有中等至高的体外活性。苯甲醛-S-4-溴苄基异硫代氰酸脒和水杨醛-S-4-氯苄基异硫代氰酸脒具有最有前途的抗分枝杆菌特性。
