University of Alberta Hospital, Edmonton, AB, Canada.
Maturitas. 2011 May;69(1):69-73. doi: 10.1016/j.maturitas.2011.02.004. Epub 2011 Mar 10.
To describe practice patterns with hormone therapy (HT) in women after a surgical menopause and to describe their experience of hot flashes and other menopausal symptoms.
This was a cross-sectional chart-review with telephone follow up interview of women between the ages of 20 and 50 years who had a hysterectomy and bilateral salpingo-oophorectomy (BSO) before menopause at an academic teaching facility in Edmonton, Canada between December 1, 2006 and November 30, 2007.
Seventy women were interviewed. Mean respondents age at surgery was 44.3 (±5.2) years and mean time since surgery was 10.2 (±3.8) months. Twenty-eight women (40%) were started on HT after surgical menopause; 23 (33%) were still taking HT at the time of the interview. Estrogen therapy (ET) was the only HT prescribed in all instances, with over half the women on transdermal estrogen at time of the interview and 70% on ET doses equivalent to 0.625mg conjugated estrogens. Women not taking HT were more likely to experience daily hot flashes (74% vs 30%, p=0.006) and to classify them as moderate or severe intensity (57% vs 47%, p=0.033). Night sweats and difficulty sleeping were reported equally in both groups.
Over 2/3rd of women were not on HT after a surgical menopause and many of these women were still having daily hot flashes. Targeted patient education prior to surgery or at discharge may help improve the management of menopausal symptoms and long term health consequences in women after a surgical menopause.
描述手术绝经后女性使用激素治疗（HT）的实践模式，并描述她们的热潮红和其他更年期症状体验。
这是一项在加拿大埃德蒙顿的一所学术教学医院进行的回顾性图表分析，通过电话随访对 2006 年 12 月 1 日至 2007 年 11 月 30 日期间绝经前接受子宫切除术和双侧输卵管卵巢切除术（BSO）的 20 至 50 岁女性进行了调查。
共对 70 名女性进行了访谈。受访者手术时的平均年龄为 44.3（±5.2）岁，手术至访谈时的平均时间为 10.2（±3.8）个月。28 名女性（40%）在手术绝经后开始接受 HT；23 名女性（33%）在访谈时仍在服用 HT。雌激素治疗（ET）是唯一开的 HT，超过一半的女性在访谈时使用透皮雌激素，70%的女性使用的 ET 剂量相当于 0.625mg 结合雌激素。未服用 HT 的女性更可能出现每日热潮红（74%比 30%，p=0.006），且更可能将其归类为中度或重度强度（57%比 47%，p=0.033）。两组均有同样比例的女性报告夜间出汗和睡眠困难。
超过 2/3 的女性在手术绝经后没有接受 HT，其中许多女性仍有每日热潮红。在手术前或出院时对患者进行有针对性的教育可能有助于改善手术绝经后女性的更年期症状和长期健康后果的管理。
