Litton Allison G, Desmond Renee A, Gilliland Janice, Huh Warner K, Franklin Frank A
Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Alabama, USA.
J Pediatr Adolesc Gynecol. 2011 Jun;24(3):166-71. doi: 10.1016/j.jpag.2011.01.004. Epub 2011 Mar 12.
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States. Adolescent and young adults aged 15-24 were estimated to account for three quarters of new infections in 2000. Two HPV vaccines are currently available. The vaccine is recommended for girls aged 11-12 years. Previous research has indicated that African-American and Asian-American parents are less likely than Caucasians to vaccinate their daughters. This investigation examines the relationship between demographic, medical, and behavioral risk factors for HPV vaccine acceptability among Alabama residents.
The cross-sectional survey was conducted using random digit dialing. Eligible participants were female caregivers of adolescent girls between the ages of 10 and 14 years. Factors related to intention to vaccinate a daughter within the next six months were examined using chi-square and logistic regression.
Caregivers who were informed about HPV vaccination from a health care provider were more likely to intend to vaccinate their daughter within the next six months compared with caregivers who did not report this source of information (OR = 3.59, 95% CI = 1.52, 8.45). Race, education, county of residence, child's age, religious attendance, knowledge and history of HPV, perceived susceptibility, and severity of infection were not significantly related to intention to vaccinate against HPV.
Caregivers who were informed of the vaccine by their health care provider were more likely to vaccinate their adolescent daughters. Provider attitudes and caregiver education is an essential link to improvement of HPV vaccination uptake in Alabama.
人乳头瘤病毒（HPV）是美国最常见的性传播感染。据估计，2000年15至24岁的青少年和年轻人占新感染病例的四分之三。目前有两种HPV疫苗可供使用。该疫苗推荐给11至12岁的女孩。先前的研究表明，非裔美国人和亚裔美国人的父母比白人父母给女儿接种疫苗的可能性更小。本调查研究了阿拉巴马州居民中HPV疫苗可接受性的人口统计学、医学和行为风险因素之间的关系。
采用随机数字拨号进行横断面调查。符合条件的参与者是10至14岁青春期女孩的女性照顾者。使用卡方检验和逻辑回归分析与在未来六个月内给女儿接种疫苗的意愿相关的因素。
与未报告此信息来源的照顾者相比，从医疗保健提供者处得知HPV疫苗接种信息的照顾者更有可能在未来六个月内打算给女儿接种疫苗（比值比=3.59，95%置信区间=1.52，8.45）。种族、教育程度、居住县、孩子年龄、宗教活动参与情况、HPV知识和病史、感知易感性以及感染严重程度与接种HPV疫苗的意愿无显著相关性。
从医疗保健提供者处得知疫苗信息的照顾者更有可能给他们的青春期女儿接种疫苗。提供者的态度和照顾者教育是提高阿拉巴马州HPV疫苗接种率的重要环节。
