Batalla A, Pérez-Pedrosa A, García-Doval I, González-Barcala F J, Rosón E, de la Torre C
Servicio de Dermatología, Complejo Hospitalario de Pontevedra, Pontevedra, España.
Actas Dermosifiliogr. 2011 Jun;102(5):373-7. doi: 10.1016/j.ad.2010.12.008. Epub 2011 Mar 12.
Pyoderma gangrenosum is a neutrophilic dermatosis that, in addition to its characteristic skin manifestations, can cause visceral alterations. Our patient was a 34-year-old woman with pyoderma gangrenosum that was exacerbated by iodine and that also affected the lungs. Other published cases of lung involvement in pyoderma gangrenosum are reviewed and we discuss the possible exacerbation of this disease by iodine. Lung involvement is the most common extracutaneous manifestation of pyoderma gangrenosum and the main differential diagnosis is then with Wegener granulomatosis. It is important to remember the possible presentation of extracutaneous manifestations of pyoderma gangrenosum, including particularly lung involvement, in order to avoid subjecting a patient to aggressive diagnostic tests, at least in the initial stages.
坏疽性脓皮病是一种嗜中性皮病,除了具有特征性的皮肤表现外,还可引起内脏改变。我们的患者是一名34岁患有坏疽性脓皮病的女性,该病因碘而加重,且累及肺部。本文回顾了其他已发表的坏疽性脓皮病累及肺部的病例,并讨论了碘可能加重该病的情况。肺部受累是坏疽性脓皮病最常见的皮肤外表现,主要鉴别诊断是韦格纳肉芽肿。重要的是要记住坏疽性脓皮病可能出现皮肤外表现,尤其是肺部受累,以便至少在初始阶段避免让患者接受侵入性诊断检查。