皮肤红斑狼疮的生活质量。
Quality of life in cutaneous lupus erythematosus.
机构信息
Philadelphia Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA.
出版信息
J Am Acad Dermatol. 2011 May;64(5):849-58. doi: 10.1016/j.jaad.2010.02.008. Epub 2011 Mar 12.
Abstract
BACKGROUND
Little is known about quality of life in patients with cutaneous lupus erythematosus.
OBJECTIVE
We sought to determine how cutaneous lupus affects quality of life and which independent variables are associated with poor quality of life.
METHODS
A total of 157 patients with cutaneous lupus completed surveys related to quality of life, including the Skindex-29 and the Short Form-36.
RESULTS
Quality of life in cutaneous lupus is severely impaired, particularly with respect to emotional well-being. Patients with cutaneous lupus have worse quality of life than those with other common dermatologic conditions, such as acne, nonmelanoma skin cancer, and alopecia. With respect to mental health status, patients with cutaneous lupus have similar or worse scores than patients with hypertension, type 2 diabetes mellitus, recent myocardial infarction, and congestive heart failure. Factors related to poor quality of life include female gender, generalized disease, severe disease, distribution of lesions, and younger age.
LIMITATIONS
The study was done at a single referral-only center.
CONCLUSION
Patients with cutaneous lupus have very impaired quality of life, particularly from an emotional perspective.
摘要
背景
对于患有红斑狼疮的患者的生活质量，我们知之甚少。
目的
我们旨在确定皮肤狼疮如何影响生活质量，以及哪些独立变量与生活质量差相关。
方法
共有 157 名患有红斑狼疮的患者完成了与生活质量相关的调查，包括 Skindex-29 和简明 36 项健康调查。
结果
红斑狼疮患者的生活质量严重受损，尤其是在情绪健康方面。与其他常见皮肤病，如痤疮、非黑色素瘤皮肤癌和脱发相比，患有红斑狼疮的患者生活质量更差。在心理健康方面，红斑狼疮患者的得分与高血压、2 型糖尿病、近期心肌梗死和充血性心力衰竭患者相似或更差。与生活质量差相关的因素包括女性、全身性疾病、严重疾病、病变分布和较年轻的年龄。
局限性
该研究仅在一个转诊中心进行。
结论
红斑狼疮患者的生活质量非常差，尤其是在情绪方面。
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