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[孕期腺苷治疗阵发性室上性心动过速后发生早产,一例报告]

[Preterm labour after adenosine treatment for paroxysmal supraventricular tachycardia during pregnancy, a case report].

作者信息

Canlorbe G, Azria E, Michel D, Iung B, Mahieu-Caputo D

机构信息

Service de gynécologie obstétrique, hôpital Bichat-Claude-Bernard, AP-HP, 46, rue Henri-Huchard, 75877 Paris cedex 18, France.

出版信息

Ann Fr Anesth Reanim. 2011 Apr;30(4):372-4. doi: 10.1016/j.annfar.2011.02.001. Epub 2011 Mar 12.

Abstract

Paroxysmal supraventricular tachycardia is the most frequent arrhythmia among young pregnant women. In case of failure of vagal manoeuvres, their management is preferentially intravenous infusion of adenosine. The in vitro contracturant effect of adenosine on myometrial fibres is known, but very few data are available about the in vivo effect during pregnancy. We report here the case of a 30-week gestational age pregnant woman treated successfully by adenosine for a junctional tachycardia. Adenosine administration was immediately followed by a preterm labour managed by calcium channels blockers tocolysis. Even if causal relationship remains uncertain, this observation is consistent with physiopathological data and should catch physician's attention when initiating this treatment.

摘要

阵发性室上性心动过速是年轻孕妇中最常见的心律失常。若迷走神经操作无效,其治疗首选静脉输注腺苷。腺苷对子宫肌层纤维的体外收缩作用是已知的,但关于孕期体内作用的数据却非常少。我们在此报告一例孕30周的孕妇,其交界性心动过速经腺苷成功治疗。给予腺苷后随即出现早产,通过钙通道阻滞剂进行了宫缩抑制治疗。即使因果关系仍不确定,但这一观察结果与生理病理数据相符,在启动该治疗时应引起医生的注意。

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