Roslin Institute and Centre for Infectious Diseases, The University of Edinburgh, Edinburgh EH164SB, United Kingdom.
J Bacteriol. 2011 May;193(9):2363-4. doi: 10.1128/JB.00137-11. Epub 2011 Mar 11.
We report the first whole-genome sequence for a clinical isolate of Staphylococcus pseudintermedius (ED99), the major pathogen responsible for canine bacterial pyoderma. S. pseudintermedius contains numerous mobile genetic elements and encodes an array of putative virulence factors, including superantigenic, cytolytic, and exfoliative toxins and cell wall-associated surface proteins.
我们报告了首个犬源中间型葡萄球菌(ED99)临床分离株的全基因组序列,该菌是引起犬细菌性脓皮病的主要病原体。中间型葡萄球菌含有大量可移动遗传元件,并编码一系列潜在的毒力因子,包括超抗原、细胞溶解和剥脱毒素以及细胞壁相关表面蛋白。