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代谢组学与外科肿瘤学:小分子生物标志物的潜在作用。

Metabolomics and surgical oncology: Potential role for small molecule biomarkers.

机构信息

Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

出版信息

J Surg Oncol. 2011 Apr;103(5):451-9. doi: 10.1002/jso.21831. Epub 2010 Dec 28.

Abstract

Metabolomics, the newest of the "omics" sciences, has brought much excitement to the field of oncology as a potential new translational tool capable of bringing the molecular world of cancer care to the bedside. While still early in its development, metabolomics could alter the scope and role of surgery in the multidisciplinary treatment of cancer. This review examines potential roles of metabolomics in areas of early cancer detection, personalized therapeutics and tumorigenesis.

摘要

代谢组学是“组学”科学中最新的一门学科,作为一种潜在的新转化工具,它为肿瘤学领域带来了很大的兴奋,使癌症护理的分子世界能够接近临床。虽然它还处于发展的早期阶段,但代谢组学可能会改变手术在癌症多学科治疗中的范围和作用。本文综述了代谢组学在早期癌症检测、个性化治疗和肿瘤发生等领域的潜在作用。

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