Sukumar Sujith, Drízhal Ivo, Bukac Josef, Paulusová Vladimíra, Pilathadka Shriharsha
Department of Dentistry, Charles University in Prague, Faculty of Medicine and University Hospital Hradec Králové, Czech Republic.
Acta Medica (Hradec Kralove). 2010;53(4):229-34.
Alloplastic bone graft materials are widely been used in combination with barrier membranes to achieve guided tissue regeneration in the treatment of periodontal intrabony defects. This study was designed to evaluate the clinical outcome of a composite material, beta tricalcium phosphate in combination with calcium sulphate in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. Thirty nine intrabony defects in 21 patients were treated with Fortoss Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated including changes in probing depth, clinical attachment level/loss and gingival recession at baseline and one year postoperatively. The mean differences in measurements between the baseline and one year postoperatively are a reduction of 1.98 +/- 1.16 mm (p = 0.000) in case of probing depth and a gain of 1.68 +/- 1.12 mm (p = 0.000) in clinical attachment level and an increase of 0.31 +/- 0.67 mm (p = 0.009) in gingival recession measurements. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects one year postoperatively.
异体骨移植材料已广泛与屏障膜联合使用，以在牙周骨内缺损的治疗中实现引导组织再生。本研究旨在评估一种复合材料，即β-磷酸三钙与硫酸钙联合使用治疗牙周骨内缺损的临床效果。由于这些材料的特性，它们的组合被认为有助于引导组织再生。对21例患者的39处骨内缺损采用Fortoss Vital（英国斯塔福德郡的Biocomposites公司生产）进行治疗。评估了临床参数，包括基线时和术后一年的探诊深度、临床附着水平/丧失以及牙龈退缩的变化。基线与术后一年测量值的平均差异为：探诊深度减少1.98±1.16毫米（p = 0.000），临床附着水平增加1.68±1.12毫米（p = 0.000），牙龈退缩测量值增加0.31±0.67毫米（p = 0.009）。研究结果表明，β-磷酸三钙与硫酸钙联合治疗在术后一年对牙周骨内缺损产生了显著良好的临床改善。
