Sukumar Sujith, Drízhal Ivo, Paulusová Vladimíra, Bukac Josef
Charles University in Prague, Faculty of Medicine, Department of Dentistry and University Hospital Hradec Králové, Czech Republic.
Acta Medica (Hradec Kralove). 2011;54(1):13-20.
The study was designed to evaluate the clinical outcome of a composite material, beta-tricalcium phosphate in combination with calcium sulphate, in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. A total of 47 teeth with intrabony defects in 26 periodontitis patients were treated with Fortoss Vital (Biocomposites, Staffordshire, U.K.). Clinical parameters were evaluated which included changes in probing depth, clinical attachment level/loss and gingival recession at the baseline and 2 years postoperatively. The mean differences in measurements between the baseline and 2 years postoperatively were a reduction of 2.07 +/- 1.14 mm (p = 0.000) in case of probing depth and a gain of 1.93 +/- 1.36 mm (p = 0.000) in clinical attachment level; but an increase of 0.14 +/- 0.73 mm (p = 0.571) in gingival recession. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects 2 years after the surgery.
本研究旨在评估一种复合材料——β-磷酸三钙与硫酸钙联合使用——治疗牙周骨内缺损的临床效果。由于这些材料的特性，它们的组合被认为有助于引导组织再生。对26名牙周炎患者的47颗患有骨内缺损的牙齿使用Fortoss Vital（英国斯塔福德郡的Biocomposites公司生产）进行治疗。评估了临床参数，包括基线时和术后2年的探诊深度、临床附着水平/丧失以及牙龈退缩的变化。基线和术后2年测量值的平均差异为：探诊深度减少2.07±1.14毫米（p = 0.000），临床附着水平增加1.93±1.36毫米（p = 0.000）；但牙龈退缩增加0.14±0.73毫米（p = 0.571）。研究结果表明，β-磷酸三钙与硫酸钙联合治疗在术后2年使牙周骨内缺损的临床状况得到了显著改善。
