Oh S J
Ann Neurol. 1977 May;1(5):481-5. doi: 10.1002/ana.410010514.
In a patient with botulism type B, electrophysiological studies showed: (1) a pattern in the repetitive nerve stimulation test resembling that found in the Eaton-Lambert syndrome but without any significant increment at high rates of stimulation or posttetanic exhaustion phenomenon; (2) a prominent response to guanidine hydrochloride; (3) a short mean duration of motor unit potentials that reversed with recovery; (4) a mild, prolonged latency and low amplitude of the H-reflex; (5) mild peripheral nerve dysfunction; and (6) a long-lasting persistence of abnormalities beyond the time of clinical recovery. The literature reports two types of responses in the repetitive nerve stimulation test in botulism: in the severe form one obtains a low-amplitude muscle potential, a decremental response at low rates of stimulation, and an insignificant incremental response at high rates of stimulation; in the mild form a normal amplitude of muscle potential occurs together with a normal response to low rates of stimulation and a significant incremental response at high rates of stimulation.
在一名B型肉毒中毒患者中，电生理研究显示：(1) 重复神经刺激试验中的模式类似于伊顿-兰伯特综合征中发现的模式，但在高频率刺激时无明显增量或强直后疲劳现象；(2) 对盐酸胍有显著反应；(3) 运动单位电位平均时限短，恢复后逆转；(4) H反射潜伏期轻度延长且波幅低；(5) 轻度周围神经功能障碍；(6) 临床恢复后异常持续很长时间。文献报道肉毒中毒重复神经刺激试验有两种反应类型：严重型表现为肌肉电位波幅低、低频率刺激时递减反应以及高频率刺激时增量反应不明显；轻度型表现为肌肉电位波幅正常、低频率刺激反应正常以及高频率刺激时有显著增量反应。
