van Nes J J, van der Most van Spijk D
Res Vet Sci. 1986 May;40(3):372-6.
In six dogs with botulism type C electrophysiological examinations showed: fibrillation potentials and prolonged insertional activity; low amplitude of the evoked muscle action potential; decrease in amplitude of the compound muscle action potential with slow repetitive stimulation; slowing of motor and sensory velocities in the peripheral nerve; and restoration of velocity and amplitude corresponding to clinical improvement. These findings indicate peripheral nerve dysfunction which cannot be explained adequately by current knowledge of the action of botulinum toxin on cholinergic nerve endings. It is therefore suggested that botulinum toxin also interferes with peripheral nerve conduction.
在6只患有C型肉毒中毒的犬中，电生理检查显示：纤颤电位和插入活动延长；诱发肌肉动作电位幅度降低；缓慢重复刺激时复合肌肉动作电位幅度降低；周围神经运动和感觉速度减慢；以及速度和幅度的恢复与临床改善相对应。这些发现表明存在周围神经功能障碍，而目前关于肉毒杆菌毒素对胆碱能神经末梢作用的知识无法充分解释这一现象。因此，有人提出肉毒杆菌毒素也会干扰周围神经传导。
