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186 株诺卡氏菌属对 20 种抗菌药物的敏感性。

Susceptibility of 186 Nocardia sp. isolates to 20 antimicrobial agents.

机构信息

Servicio de Microbiología-Instituto Biodonostia, Hospital Donostia, San Sebastián, Spain.

出版信息

Antimicrob Agents Chemother. 2011 Jun;55(6):2995-8. doi: 10.1128/AAC.01279-10. Epub 2011 Mar 14.

DOI:10.1128/AAC.01279-10
PMID:21402847
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3101401/
Abstract

This study determined the antimicrobial susceptibilities of 186 clinical isolates of Nocardia spp. isolated in Gipuzkoa, northern Spain, between 1998 and 2009. Most isolates were recovered from respiratory samples, Nocardia nova, N. farcinica, N. cyriacigeorgica, N. abscessus, and N. carnea being the species most frequently isolated. Linezolid and amikacin were the only two antimicrobials to which all isolates were susceptible. The majority of N. flavorosea, N. carnea, and N. farcinica isolates were trimethoprim-sulfamethoxazole resistant.

摘要

本研究确定了 1998 年至 2009 年间在西班牙北部吉普斯夸（Gipuzkoa）分离的 186 株诺卡氏菌属临床分离株的抗菌药敏性。大多数分离株来自呼吸道样本，最常分离到的菌种为新星诺卡氏菌（N. nova）、星形诺卡氏菌（N. farcinica）、细弱诺卡氏菌（N. cyriacigeorgica）、脓肿诺卡氏菌（N. abscessus）和肉色诺卡氏菌（N. carnea）。利奈唑胺和阿米卡星是所有分离株均敏感的仅有的两种抗菌药物。大多数芬芳诺卡氏菌（N. flavorosea）、肉色诺卡氏菌和星形诺卡氏菌分离株对甲氧苄啶-磺胺甲恶唑耐药。

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