Leffler Christopher T, Wilkes Martin, Reeves Juliana, Mahmood Muneera A
Ophthalmology Section, Hunter Holmes McGuire Veterans Affairs Medical Center, and Department of Ophthalmology, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23249, USA.
Arch Ophthalmol. 2011 Mar;129(3):295-300. doi: 10.1001/archophthalmol.2010.375.
To predict postoperative refractive astigmatism in the second eye undergoing cataract surgery using standard biometry and information obtained from the first eye.
We conducted a retrospective study of 160 patients undergoing bilateral sequential phacoemulsification with capsular bag implantation of a hydrophobic acrylic lens at a Veterans Affairs medical center. Keratometric and refractive astigmatism were described by Jackson cross cylinder with-the-rule (J(0)) and oblique (J(X)) components. Preoperative predictors of postoperative refractive astigmatism in the second eye were determined by multivariable regression.
The postoperative refractive astigmatism in the first eye predicted 40% of the variation in the second eye (r(2) = 0.40; P < .001). The multivariable model to predict postoperative with-the-rule astigmatism was J(0PostopEye2) = (0.376 × J(0PostopEye1)) + (0.327 × J(0KeratomEye2)) + (0.097 × J(0PreopEye2)) - 0.099 (P < .001 for first 2 terms; r(2) = 0.56). The multivariable model for oblique astigmatism was J(XPostopEye2) = (0.350 × J(XKeratomEye2)) + (0.231 × J(XKeratomEye1)) + (0.064 × J(XPreopEye2)) - 0.07 (P ≤ .01 for first 2 terms; r(2) = 0.20).
Refractive with-the-rule astigmatism observed postoperatively in the first eye is a strong independent predictor of postoperative with-the-rule astigmatism in the second eye. Keratometric oblique astigmatism in the first eye is a weak but statistically significant independent predictor of postoperative oblique astigmatism in the second eye. Both findings are consistent with mirror symmetry of the corneas about the midsagittal plane and may improve the prediction (and hence control) of postoperative astigmatism in the second eye.