甲硝唑导致血清谷草转氨酶假性降低。
Artifactual depression of serum glutamic oxaloacetic transaminase by metronidazole.
作者信息
Rissing J P, Newman C, Moore W L
出版信息
Antimicrob Agents Chemother. 1978 Oct;14(4):636-8. doi: 10.1128/AAC.14.4.636.
Abstract
Eighteen patients developed abnormally low serum glutamic oxaloacetic transaminase values during metronidazole therapy. Metronidazole absorbs at 340 nm, simulating reduced nicotinamide adenine dinucleotide, which is the final colorimetric product of the serum glutamic oxaloacetic transaminase assay.
摘要
18名患者在甲硝唑治疗期间出现血清谷氨酸草酰乙酸转氨酶值异常降低。甲硝唑在340nm处有吸收，模拟还原型烟酰胺腺嘌呤二核苷酸，而还原型烟酰胺腺嘌呤二核苷酸是血清谷氨酸草酰乙酸转氨酶测定的最终比色产物。
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