Bishop P E, McMillan A, Fletcher S
Department of Medicine, Edinburgh Royal Infirmary, UK.
Genitourin Med. 1990 Apr;66(2):79-81. doi: 10.1136/sti.66.2.79.
An immunohistological study of four men whose perianal warts were undergoing spontaneous regression was undertaken, and the results compared with those obtained from non-regressing condylomata from six men. CD4+ and CD8+ cells were noted in the stroma of each wart, but there was no clear difference in the density of the infiltrate between regressing and non-regressing warts. Natural killer cells (CD16+ and CD57+) were only noted in the stroma and epidermis of regressing warts. Possible immunological mechanisms of regression of condylomata acuminata are discussed.
对4名肛周疣正在自然消退的男性进行了免疫组织学研究,并将结果与6名疣未消退男性的尖锐湿疣结果进行比较。在每个疣体的基质中均发现CD4 +和CD8 +细胞,但消退和未消退疣体之间浸润密度无明显差异。自然杀伤细胞(CD16 +和CD57 +)仅在消退疣体的基质和表皮中发现。本文讨论了尖锐湿疣消退可能的免疫机制。