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1
Good COP1 or bad COP1? In vivo veritas.
J Clin Invest. 2011 Apr;121(4):1263-5. doi: 10.1172/JCI57080. Epub 2011 Mar 14.
2
Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.
J Clin Invest. 2011 Apr;121(4):1329-43. doi: 10.1172/JCI45784. Epub 2011 Mar 14.
4
ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.
Science. 2006 Aug 25;313(5790):1122-6. doi: 10.1126/science.1127335.
5
The ubiquitin ligase COP1 is a critical negative regulator of p53.
Nature. 2004 May 6;429(6987):86-92. doi: 10.1038/nature02514. Epub 2004 Apr 21.
7
The Ubiquitin Ligase COP1 Promotes Glioma Cell Proliferation by Preferentially Downregulating Tumor Suppressor p53.
Mol Neurobiol. 2017 Sep;54(7):5008-5016. doi: 10.1007/s12035-016-0033-x. Epub 2016 Aug 17.
8
Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates.
Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4078-4087. doi: 10.1073/pnas.1913698117. Epub 2020 Feb 10.
10
COP1 - from plant photomorphogenesis to mammalian tumorigenesis.
Trends Cell Biol. 2005 Nov;15(11):618-25. doi: 10.1016/j.tcb.2005.09.007. Epub 2005 Sep 29.

引用本文的文献

1
In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target.
Cell. 2021 Oct 14;184(21):5357-5374.e22. doi: 10.1016/j.cell.2021.09.006. Epub 2021 Sep 27.
2
EGF Relays Signals to COP1 and Facilitates FOXO4 Degradation to Promote Tumorigenesis.
Adv Sci (Weinh). 2020 Sep 23;7(20):2000681. doi: 10.1002/advs.202000681. eCollection 2020 Oct.
3
Regulation of the p53 Family Proteins by the Ubiquitin Proteasomal Pathway.
Int J Mol Sci. 2019 Dec 30;21(1):261. doi: 10.3390/ijms21010261.
4
CRY arrests Cop1 to regulate circadian rhythms in mammals.
Cell Div. 2019 Nov 2;14:12. doi: 10.1186/s13008-019-0055-7. eCollection 2019.
5
Correlation of constitutive photomorphogenic 1 (COP1) and p27 tumor suppressor protein expression in ovarian cancer.
Genes Genomics. 2019 Aug;41(8):879-884. doi: 10.1007/s13258-019-00818-6. Epub 2019 Apr 26.
7
HuCOP1 contributes to the regulation of DNA repair in keratinocytes.
Mol Cell Biochem. 2017 Mar;427(1-2):103-109. doi: 10.1007/s11010-016-2901-0. Epub 2016 Dec 19.
8
The Ubiquitin Ligase COP1 Promotes Glioma Cell Proliferation by Preferentially Downregulating Tumor Suppressor p53.
Mol Neurobiol. 2017 Sep;54(7):5008-5016. doi: 10.1007/s12035-016-0033-x. Epub 2016 Aug 17.
9
High expression of constitutive photomorphogenic 1 (COP1) is associated with poor prognosis in bladder cancer.
Tumour Biol. 2016 Jul;37(7):8917-22. doi: 10.1007/s13277-015-4765-4. Epub 2016 Jan 11.
10
COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.
Oncotarget. 2015 Aug 14;6(23):19721-34. doi: 10.18632/oncotarget.3821.

本文引用的文献

1
Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.
J Clin Invest. 2011 Apr;121(4):1329-43. doi: 10.1172/JCI45784. Epub 2011 Mar 14.
3
The E3 ubiquitin ligase complex component COP1 regulates PEA3 group member stability and transcriptional activity.
Oncogene. 2010 Mar 25;29(12):1810-20. doi: 10.1038/onc.2009.471. Epub 2010 Jan 11.
4
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1.
Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17493-8. doi: 10.1073/pnas.0908027106. Epub 2009 Sep 24.
5
RING domain E3 ubiquitin ligases.
Annu Rev Biochem. 2009;78:399-434. doi: 10.1146/annurev.biochem.78.101807.093809.
6
COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression.
J Biol Chem. 2008 Dec 19;283(51):35464-73. doi: 10.1074/jbc.M801011200. Epub 2008 Sep 24.
8
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
Nature. 2007 Sep 20;449(7160):366-9. doi: 10.1038/nature06128. Epub 2007 Sep 5.
10
ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.
Science. 2006 Aug 25;313(5790):1122-6. doi: 10.1126/science.1127335.

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