[幽门螺杆菌感染在血液系统疾病中的作用——综述]

[The role of Helicobacter pylori infection in hematological diseases - a review].

作者信息

Sato Kazuya, Ozawa Keiya

机构信息

Division of Hematology, Dept. of Medicine, Jichi Medical University, Japan.

出版信息

Gan To Kagaku Ryoho. 2011 Mar;38(3):358-61.

PMID:21403437

Abstract

Helicobacter pylori (H. pylori) infection has been known to be the most closely associated with extra-gastrointestinal diseases. Above all, the association between H. pylori and hematological diseases, including immune thrombocytopenic purpura ( ITP), gastric MALT lymphoma and iron deficiency anemia (IDA) has been focused. Although the molecular mechanisms have not yet been fully understood, H. pylori eradication resulted in high response rates without major adverse effects. We focus here on a comprehensive review of the current literature of ITP, gastric MALT lymphoma and IDA.

摘要

幽门螺杆菌（H. pylori）感染已知与胃肠道外疾病关系最为密切。最重要的是，幽门螺杆菌与血液系统疾病之间的关联受到关注，这些疾病包括免疫性血小板减少性紫癜（ITP）、胃黏膜相关淋巴组织淋巴瘤（MALT淋巴瘤）和缺铁性贫血（IDA）。尽管其分子机制尚未完全明确，但根除幽门螺杆菌可带来高缓解率且无重大不良反应。我们在此着重对目前关于ITP、胃MALT淋巴瘤和IDA的文献进行全面综述。