Pauszek M E
Indiana Med. 1990 May;83(5):330-1.
The ampicillin analog, amoxicillin, can potentially produce the same hypersensitivity reaction as the ampicillin. The case of a patient treated with amoxicillin for a sore throat, who later presented with a rash, is reviewed. Infectious mononucleosis was considered and then supported by a positive mono spot. It would appear therefore that amoxicillin can produce the same hypersensitivity reaction as ampicillin in the setting of acute infectious mononucleosis. The clinical decision to use antibiotics in acute pharyngitis is complicated by the identical presentation of both viral and bacterial illnesses. If empiric therapy is elected, the incidence of hypersensitivity reaction is less common with penicillin or tetracycline compared to ampicillin or its analog, amoxicillin.
氨苄西林类似物阿莫西林可能会引发与氨苄西林相同的过敏反应。本文回顾了一名因喉咙痛接受阿莫西林治疗、随后出现皮疹的患者病例。考虑到感染性单核细胞增多症，随后单核细胞斑点试验呈阳性进一步证实了该诊断。因此，在急性感染性单核细胞增多症的情况下，阿莫西林似乎会引发与氨苄西林相同的过敏反应。急性咽炎中使用抗生素的临床决策因病毒和细菌疾病表现相同而变得复杂。如果选择经验性治疗，与氨苄西林或其类似物阿莫西林相比，青霉素或四环素引起过敏反应的发生率较低。
