Suppr超能文献

帕金森病患者丘脑底核深部脑刺激术后的冲动控制障碍:临床方面。

Impulse control disorders following deep brain stimulation of the subthalamic nucleus in Parkinson's disease: clinical aspects.

机构信息

University of Birmingham Medical School, Birmingham B152TT, UK.

出版信息

Parkinsons Dis. 2011 Feb 20;2011:658415. doi: 10.4061/2011/658415.

Abstract

Parkinson's disease (PD) has been associated with the development of impulse control disorders (ICDs), possibly due to overstimulation of the mesolimbic system by dopaminergic medication. Preliminary reports have suggested that deep brain stimulation (DBS), a neurosurgical procedure offered to patients with treatment-resistant PD, affects ICD in a twofold way. Firstly, DBS allows a decrease in dopaminergic medication and hence causes an improvement in ICDs. Secondly, some studies have proposed that specific ICDs may develop after DBS. This paper addresses the effects of DBS on ICDs in patients with PD. A literature search identified four original studies examining a total of 182 patients for ICDs and nine case reports of 39 patients that underwent DBS and developed ICDs at some point. Data analysis from the original studies did not identify a significant difference in ICDs between patients receiving dopaminergic medication and patients on DBS, whilst the case reports showed that 56% of patients undergoing DBS had poor outcome with regards to ICDs. We discuss these ambivalent findings in the light of proposed pathogenetic mechanisms. Longitudinal, prospective studies with larger number of patients are required in order to fully understand the role of DBS on ICDs in patients with PD.

摘要

帕金森病(PD)与冲动控制障碍(ICD)的发展有关,可能是由于多巴胺能药物对中脑边缘系统的过度刺激。初步报告表明,深部脑刺激(DBS)是一种为治疗抵抗性 PD 患者提供的神经外科手术,以双重方式影响 ICD。首先,DBS 允许减少多巴胺能药物,从而导致 ICD 改善。其次,一些研究提出特定的 ICD 可能在 DBS 后发展。本文探讨了 DBS 对 PD 患者 ICD 的影响。文献检索确定了四项原始研究,共检查了 182 例 ICD 患者,以及 9 例 39 例接受 DBS 并在某个时间点发生 ICD 的病例报告。原始研究的数据分析并未发现接受多巴胺能药物治疗的患者与接受 DBS 的患者之间 ICD 存在显著差异,而病例报告表明,56%的接受 DBS 的患者在 ICD 方面预后不佳。我们根据提出的发病机制讨论了这些矛盾的发现。需要进行更多患者的纵向、前瞻性研究,以充分了解 DBS 在 PD 患者 ICD 中的作用。

相似文献

2
A 7-year observation of the effect of subthalamic deep brain stimulation on impulse control disorder in patients with Parkinson's disease.
Parkinsonism Relat Disord. 2018 Nov;56:3-8. doi: 10.1016/j.parkreldis.2018.07.010. Epub 2018 Jul 20.
3
Subthalamic nucleus stimulation and compulsive use of dopaminergic medication in Parkinson's disease.
J Neurol Neurosurg Psychiatry. 2013 Aug;84(8):868-74. doi: 10.1136/jnnp-2012-302387. Epub 2013 Feb 27.
5
Management of impulse control disorders with deep brain stimulation: A double-edged sword.
J Neurol Sci. 2017 Mar 15;374:63-68. doi: 10.1016/j.jns.2017.01.019. Epub 2017 Jan 7.
7
Course of Impulse Control Disorder Symptoms in Parkinson's Disease: Deep Brain Stimulation Versus Medications.
Mov Disord Clin Pract. 2023 May 5;10(6):903-913. doi: 10.1002/mdc3.13738. eCollection 2023 Jun.
8
Subthalamic deep brain stimulation and impulse control in Parkinson's disease.
Eur J Neurol. 2009 Apr;16(4):493-7. doi: 10.1111/j.1468-1331.2008.02509.x.
9
Measures of impulsivity in Parkinson's disease decrease after DBS in the setting of stable dopamine therapy.
Parkinsonism Relat Disord. 2017 Nov;44:13-17. doi: 10.1016/j.parkreldis.2017.08.006. Epub 2017 Aug 9.
10
Dopamine dysregulation syndrome, impulse control disorders and punding after deep brain stimulation surgery for Parkinson's disease.
J Clin Neurosci. 2009 Sep;16(9):1148-52. doi: 10.1016/j.jocn.2008.12.010. Epub 2009 Jun 23.

引用本文的文献

1
Morphometric alterations of the mesocorticolimbic network in Parkinson's disease with impulse control disorders.
J Neural Transm (Vienna). 2024 Mar;131(3):229-237. doi: 10.1007/s00702-023-02735-1. Epub 2024 Jan 12.
2
Earlier Intervention with Deep Brain Stimulation for Parkinson's Disease.
Parkinsons Dis. 2017;2017:9358153. doi: 10.1155/2017/9358153. Epub 2017 Aug 16.
3
Measures of impulsivity in Parkinson's disease decrease after DBS in the setting of stable dopamine therapy.
Parkinsonism Relat Disord. 2017 Nov;44:13-17. doi: 10.1016/j.parkreldis.2017.08.006. Epub 2017 Aug 9.
4
Deep-Brain Stimulation of the Subthalamic Nucleus Selectively Decreases Risky Choice in Risk-Preferring Rats.
eNeuro. 2017 Aug 7;4(4). doi: 10.1523/ENEURO.0094-17.2017. eCollection 2017 Jul-Aug.
5
The effect of deep brain stimulation on the non-motor symptoms of Parkinson's disease: a critical review of the current evidence.
NPJ Parkinsons Dis. 2017 Jan 12;3:16024. doi: 10.1038/npjparkd.2016.24. eCollection 2017.
6
Impulse Control Disorders and Related Complications of Parkinson's Disease Therapy.
Semin Neurol. 2017 Apr;37(2):186-192. doi: 10.1055/s-0037-1601887. Epub 2017 May 16.
7
Pathological gambling in Parkinson's disease: what are the risk factors and what is the role of impulsivity?
Eur J Neurosci. 2017 Jan;45(1):67-72. doi: 10.1111/ejn.13396. Epub 2016 Oct 1.
8
No Effect of Subthalamic Deep Brain Stimulation on Intertemporal Decision-Making in Parkinson Patients.
eNeuro. 2016 May 23;3(2). doi: 10.1523/ENEURO.0019-16.2016. eCollection 2016 Mar-Apr.
9
The Subthalamic Nucleus, Limbic Function, and Impulse Control.
Neuropsychol Rev. 2015 Dec;25(4):398-410. doi: 10.1007/s11065-015-9306-9. Epub 2015 Nov 14.
10
The treatment of Parkinson's disease with deep brain stimulation: current issues.
Neural Regen Res. 2015 Jul;10(7):1018-22. doi: 10.4103/1673-5374.160094.

本文引用的文献

1
Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients.
Arch Neurol. 2010 May;67(5):589-95. doi: 10.1001/archneurol.2010.65.
2
Parkinson's disease dementia.
Curr Neurol Neurosci Rep. 2010 Jul;10(4):292-8. doi: 10.1007/s11910-010-0113-7.
3
Thalamic deep brain stimulation for treatment-refractory Tourette syndrome: two-year outcome.
Neurology. 2009 Oct 27;73(17):1375-80. doi: 10.1212/WNL.0b013e3181bd809b.
4
Impulse control disorders in Parkinson's disease in a Chinese population.
Neurosci Lett. 2009 Nov 6;465(1):6-9. doi: 10.1016/j.neulet.2009.06.074. Epub 2009 Jun 26.
5
Dopamine dysregulation syndrome, impulse control disorders and punding after deep brain stimulation surgery for Parkinson's disease.
J Clin Neurosci. 2009 Sep;16(9):1148-52. doi: 10.1016/j.jocn.2008.12.010. Epub 2009 Jun 23.
6
Dopamine agonists and therapy compliance.
Neurol Sci. 2008 Dec;29 Suppl 5:S375-6. doi: 10.1007/s10072-008-1050-y.
7
Subthalamic deep brain stimulation and impulse control in Parkinson's disease.
Eur J Neurol. 2009 Apr;16(4):493-7. doi: 10.1111/j.1468-1331.2008.02509.x.
8
Hypersexuality following subthalamic nucleus stimulation for Parkinson's disease.
Neurol India. 2008 Oct-Dec;56(4):474-6. doi: 10.4103/0028-3886.44830.
9
[Pathological gambling and Parkinson disease].
Brain Nerve. 2008 Sep;60(9):1039-46.
10
[Impulse control disorders and Parkinson's disease].
Rev Med Suisse. 2008 May 7;4(156):1145-8, 1150.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验