光诱导粗糙脉孢菌野生型菌株中一种33 kDa蛋白质的去磷酸化：调控突变体wc-1和wc-2表现异常。

Light-induced dephosphorylation of a 33 kDa protein in the wild-type strain of Neurospora crassa: the regulatory mutants wc-1 and wc-2 are abnormal.

作者信息

Lauter F R, Russo V E

机构信息

Max-Planck-Institut für Molekulare Genetik, Berlin, F.R.G.

出版信息

J Photochem Photobiol B. 1990 Apr 1;5(1):95-103. doi: 10.1016/1011-1344(90)85008-k.

DOI:10.1016/1011-1344(90)85008-k

PMID:2140412

Abstract

Light induces the dephosphorylation of a 33 kdalton protein within 8 min in the wild-type strain of Neurospora crassa. The regulatory mutants, wc-1 and wc-2, have an altered pattern of phosphoproteins in darkness and also after irradiation. Because the wc genes have previously been implicated in photodifferentiation (F. Degli Innocenti and V. E. A. Russo, Genetic analysis of blue light-induced responses in Neurospora crassa, in H. Senger (ed.), Blue Light Effects in Biological Systems, Springer-Verlag, Berlin, Heidelberg, 1984, pp. 213-219), we suggest that protein dephosphorylation may constitute a necessary step in the light-transduction chain of Neurospora crassa.

摘要

在粗糙脉孢菌的野生型菌株中，光在8分钟内诱导一种33千道尔顿蛋白质的去磷酸化。调控突变体wc-1和wc-2在黑暗中以及照射后具有改变的磷蛋白模式。由于wc基因先前已被认为与光分化有关（F. Degli Innocenti和V. E. A. Russo，粗糙脉孢菌蓝光诱导反应的遗传分析，载于H. Senger编著的《生物系统中的蓝光效应》，施普林格出版社，柏林，海德堡，1984年，第213 - 219页），我们认为蛋白质去磷酸化可能是粗糙脉孢菌光转导链中的一个必要步骤。