Department of Phytochemistry, Guangxi Institute of Botany, Guangxi Zhuangzu Autonomous Region and Chinese Academy of Sciences, Guilin 541006, P R China.
Chem Biodivers. 2011 Mar;8(3):460-6. doi: 10.1002/cbdv.201000035.
Three new pregnane glycosides, 3-O-β-D-glucopyranosyl-(1→2)-α-L-arabinopyranosyl-(20R)-pregn-5-ene-3β,20-diol (1), 3-O-α-L-arabinopyranosyl-(20R)-pregn-5-ene-3β,20-diol-20-O-β-D-glucopyranoside (2), 3-O-α-L-arabinopyranosyl-(20R)-pregn-5-ene-3β,20-diol-20-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (3) were isolated along with four known compounds, 4-7, from the leaves and stems of Brucea javanica. Their structures were determined by detailed analyses of 1D- and 2D-NMR spectroscopic data. All of the compounds isolated from Brucea javanica were tested for the antifeedant activities against the larva of Pieris rapae. Compounds 1, 3, and 5 showed significant antifeedant activities after 72 h incubation.
从苦木科鸦胆子属植物鸦胆子的叶和茎中分离得到三个新的孕甾烷糖苷，分别为 3-O-β-D-吡喃葡萄糖基-(1→2)-α-L-阿拉伯吡喃糖基-(20R)-孕甾-5-烯-3β,20-二醇（1）、3-O-α-L-阿拉伯吡喃糖基-(20R)-孕甾-5-烯-3β,20-二醇-20-O-β-D-吡喃葡萄糖苷（2）和 3-O-α-L-阿拉伯吡喃糖基-(20R)-孕甾-5-烯-3β,20-二醇-20-O-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖苷（3），此外还分离得到四个已知化合物 4-7。通过对 1D-和 2D-NMR 波谱数据分析，确定了它们的结构。从鸦胆子中分离得到的所有化合物均进行了对菜青虫幼虫的拒食活性测试。在孵育 72 h 后，化合物 1、3 和 5 表现出显著的拒食活性。
