Appalup M V, Rogachevskiĭ O V, Fedorova T A, Sokologorskiĭ S V
Anesteziol Reanimatol. 2010 Nov-Dec(6):51-5.
The article presents a clinical investigation of two incidents of Transfusion Related Acute Lung Injury (TRALI) which have occurred after the fresh frozen plasma (FFP) transfusion in puerperant. According to evidence, when in timely diagnosed, the TRALI treatment is not complicated and lies in symptomatic lung oedema treatment. The incidence of TRALI in V.I. Kulakov Research Center of Obstetrics, Gynaecology, and Perinatology is estimated as 1 event out of the 699.5 transfused FFP doses per year. Among of the most promising methods of reducing the risk of TRALI and other transfusion related complications are: reduction of donor blood transfusion, introduction of autohaemodonorship and education of physicians working in obstetrics.
本文介绍了两例产后新鲜冰冻血浆（FFP）输血后发生的输血相关急性肺损伤（TRALI）的临床调查。有证据表明，TRALI若能及时诊断，治疗并不复杂，主要是对症治疗肺水肿。据估计，VI库拉科夫妇产科和围产医学研究中心TRALI的发生率为每年每699.5剂FFP输血中有1例。降低TRALI和其他输血相关并发症风险的最有前景的方法包括：减少供体输血、引入自体输血以及对产科医生进行教育。
