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[胸腔孤立性纤维瘤]

[Solitary fibrous tumor of pleural cavity].

作者信息

Szkorupa M, Klein J, Bohanes T, Neoral C, Chudácek J

机构信息

I. Chirurgická klinika LF UP a FN v Olomouci.

出版信息

Rozhl Chir. 2010 Dec;89(12):750-3.

PMID:21404515
Abstract

INTRODUCTION

Solitary fibrous pleural tumor (SFT) is, in most cases, a benign tumor arising from mesenchymal cells. A malignant version of the tumor is rare and its histopathological evaluation is quite difficult. Usually, SFT affects visceral, as well as parietal pleura, most commonly in a form of a pedunculated tumor. The treatment is primarily surgical, with the aim to perform radical resection even in case of infiltrative growth. Adjuvant therapy is indicated in malignant varieties of the tumor, however, its outcome is uncertain. SFTs have fairly high relaps rates and their prognosis and the risk of relaps can be estimated based on morphological indicators and assessment of their biological characteristics.

AIM

Retrospective analysis of SFT group of patients, who were operated from 2006 to 2009.

SUBJECTS AND METHODS

The authors present a group of 11 patients with solitary fibrous pleural tumors, who were operated at the Ist Faculty Hospital Surgical Clinic of the LF UP (Medical Faculty of the Palacky University) in Olomouc from 2006 to 2009. The authors assessed the patient's age, size of the tumors, types of the procedures, biological characteristics of the tumors, duration of hospitalization and complication rates.

CONCLUSION

Solitary pleural tumors are fairly rare tumors arising from fibroblastic cells, Its biological characteristics is uncertain and, in some cases, is difficult to assess based on immunohistochemical, as well as morphological indicators. The treatment is surgical--removal of the tumor as far as the healthy tissue. Adjuvant therapy is indicated in malignant varieties of the tumor. SFT relaps rate is fairly high, depending on the tumor biological characteristics and its morphological features.

摘要

引言

孤立性纤维性胸膜肿瘤(SFT)在大多数情况下是一种起源于间充质细胞的良性肿瘤。该肿瘤的恶性形式较为罕见,其组织病理学评估相当困难。通常,SFT会累及脏层和壁层胸膜,最常见的表现形式是带蒂肿瘤。治疗主要采用手术方式,即便肿瘤呈浸润性生长,也旨在进行根治性切除。对于肿瘤的恶性类型,需进行辅助治疗,然而其疗效尚不确定。SFT的复发率相当高,可根据形态学指标及其生物学特性评估来估计其预后和复发风险。

目的

对2006年至2009年接受手术治疗的SFT患者组进行回顾性分析。

对象与方法

作者呈现了一组11例孤立性纤维性胸膜肿瘤患者,他们于2006年至2009年在奥洛穆茨的帕拉茨基大学医学院第一附属医院外科诊所接受手术。作者评估了患者的年龄、肿瘤大小、手术方式、肿瘤的生物学特性、住院时间和并发症发生率。

结论

孤立性胸膜肿瘤是起源于成纤维细胞的相当罕见的肿瘤,其生物学特性尚不确定,在某些情况下,基于免疫组化以及形态学指标难以评估。治疗方式为手术——切除肿瘤直至健康组织。对于肿瘤的恶性类型,需进行辅助治疗。SFT的复发率相当高,这取决于肿瘤的生物学特性及其形态特征。

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