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通过激光多普勒血流仪测量的羔羊头皮血流量以及经皮氧分压和二氧化碳分压。

Scalp blood flow, measured by laser Doppler flowmetry, and transcutaneous PO2 and PCO2 in the lamb.

作者信息

Smits T M, Aarnoudse J G, Zijlstra W G

机构信息

Department of Obstetrics and Gynecology, University Hospital Groningen, The Netherlands.

出版信息

Pediatr Res. 1990 May;27(5):442-4. doi: 10.1203/00006450-199005000-00005.

DOI:10.1203/00006450-199005000-00005
PMID:2140600
Abstract

To describe the relation between scalp blood flow and transcutaneous PO2 and PCO2, these three signals were recorded simultaneously in eight experiments on four healthy lambs in the first weeks after birth. Scalp blood flow was recorded by a laser Doppler flow sensor that was incorporated in the transcutaneous PO2 electrode. Scalp blood flow was varied by applying a circular pressure on the scalp surrounding the sensors. A decrease in laser Doppler blood flow was associated with a decrease in transcutaneous PO2 and an increase in transcutaneous PCO2, according to a hyperbolic curve. The steep parts of the hyperbolic curves were observed at low scalp blood flow, whereas the flat parts were found at high flow values. Even during heat-induced hyperemia only a small part of these hyperbolic curves showed a reasonable independence of the transcutaneous blood gas values of changes in blood flow. In view of the previously observed decrease in intrapartum scalp blood flow, the present data render the transcutaneous measurement of blood gas values doubtful for fetal monitoring during labor.

摘要

为描述头皮血流与经皮氧分压(PO2)和二氧化碳分压(PCO2)之间的关系,在出生后第一周对4只健康羔羊进行了8次实验,同时记录了这三种信号。头皮血流由集成在经皮PO2电极中的激光多普勒血流传感器记录。通过对传感器周围的头皮施加环形压力来改变头皮血流。根据双曲线曲线,激光多普勒血流的减少与经皮PO2的降低和经皮PCO2的升高相关。双曲线曲线的陡峭部分出现在低头皮血流时,而平坦部分出现在高血流值时。即使在热诱导的充血期间,这些双曲线曲线中只有一小部分显示出经皮血气值对血流变化具有合理的独立性。鉴于先前观察到的产时头皮血流减少,目前的数据使得在分娩期间对胎儿进行血气值的经皮测量用于监测存疑。

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