Transplant Center, Fuzhou Medical College, Fuzhou General Hospital, Second Military Medical University, Fuzhou, China.
Diabetes Technol Ther. 2011 May;13(5):537-41. doi: 10.1089/dia.2010.0173. Epub 2011 Mar 15.
Recently a considerable number of promising clinical trials have been designed to perform infusion of stem cells by pancreatic arterial intervention to improve the endocrine function of the pancreas for better diabetes control. It is necessary to investigate the pancreatic body and tail (PBT) arterial system for human islets located mostly in the PBT and identify the predominant artery or arteries. However, the arterial system in the PBT is complicated and variable. In this study we comprehensively investigated the anatomical characteristics of arteries feeding the PBT.
One hundred two patients with diabetes underwent 64-slice computed tomography angiography (CTA) and digital subtraction angiography (DSA). The target artery was catheterized, and DSA was performed to show the PBT. All images were documented for later analysis.
DSA demonstrated that the feeding arteries for the PBT included the dorsal pancreatic artery (DPA) alone (n = 51 [50%]), combined DPA and great pancreatic artery (GPA) (n = 22 [21.6%]), GPA alone (n = 16 [15.7%]), and transverse pancreatic artery (TPA) (n = 11 [10.8%]). DPA was observed to originate from the initial segment of the splenic artery (n = 34 [46.6%]), common hepatic artery (n = 17 [23.3%]), or superior mesenteric artery (n = 14 [19.2%]). The GPA was mostly from the middle (n = 36 [94.7%]), and only two were found to originate from the initial segment of the splenic artery. The TPA (n = 11) was from either the pancreatoduodenal artery (n = 5 [54.5%]) or the gastroduodenal artery (n = 4 [36.4%]). In most case, the predominant artery of the PBT (95.1%, 97 of 102) could be revealed by 64-slice CTA.
The origins and identities of the predominant artery in the PBT are variable. DSA is superior to CTA for preoperative imaging in arterial intervention therapy.
最近，许多有前途的临床试验旨在通过胰腺动脉介入输注干细胞，以改善胰腺的内分泌功能，从而更好地控制糖尿病。有必要研究人体胰岛主要位于胰体尾部（PBT）的 PBT 动脉系统，并确定优势动脉或动脉。然而，PBT 的动脉系统复杂且多变。在这项研究中，我们全面研究了供应 PBT 的动脉的解剖学特征。
102 例糖尿病患者行 64 层 CT 血管造影（CTA）和数字减影血管造影（DSA）。目标动脉插管，行 DSA 显示 PBT。所有图像均记录以备后用。
DSA 显示，PBT 的供血动脉包括单独的胰背动脉（DPA）（n = 51 [50%]）、DPA 和大胰动脉（GPA）联合（n = 22 [21.6%]）、单独 GPA（n = 16 [15.7%]）和横胰动脉（TPA）（n = 11 [10.8%]）。DPA 观察到起源于脾动脉初始段（n = 34 [46.6%]）、肝总动脉（n = 17 [23.3%]）或肠系膜上动脉（n = 14 [19.2%]）。GPA 主要来自中（n = 36 [94.7%]），仅 2 例来自脾动脉起始段。TPA（n = 11）来自胰十二指肠动脉（n = 5 [54.5%]）或胃十二指肠动脉（n = 4 [36.4%]）。在大多数情况下（95.1%，102 例中的 97 例），64 层 CTA 可显示 PBT 的优势动脉。
PBT 优势动脉的起源和身份各不相同。DSA 优于 CTA 用于动脉介入治疗的术前成像。
