Department of Cardiology, Isala Klinieken, Groot Wezenland 20, 8011JW, Zwolle, The Netherlands.
Eur Heart J. 2011 Jun;32(11):1362-8. doi: 10.1093/eurheartj/ehr048. Epub 2011 Mar 15.
A recent report of the EuroHeart project has shown that women are still underrepresented in many cardiovascular clinical trials, while important gender differences are present within most areas of heart disease. As the burden of cardiovascular disease is increasing in middle-aged women relative to men, a more profound understanding is needed of the fundamental biological differences that exist between men and women. In the current review, we aim to address the need for more explanatory sex-specific cardiovascular research to be able to adapt existing guidelines for a better heart health in women.
最近的 EuroHeart 项目报告显示，女性在许多心血管临床试验中的代表性仍然不足，而在大多数心脏病领域都存在重要的性别差异。由于心血管疾病的负担在中年女性中相对于男性而言正在增加，因此需要更深入地了解男性和女性之间存在的基本生物学差异。在本次综述中，我们旨在满足需要更多解释性的特定性别心血管研究的需求，以便能够调整现有的指南，以实现女性更好的心脏健康。
