Alansare Abdullah Bandar, Alotaibi Rawan Tuayes, Albarrati Ali Mufrih, Stoner Lee, Gibbs Bethany Barone
Department of Exercise Physiology, College of Sport Sciences and Physical Activity, King Saud University, King Khalid Rd., Riyadh 80200, Saudi Arabia.
Rehabilitation Sciences Department, College of Applied Medical Sciences, King Saud University, King Khalid Rd., Riyadh 80200, Saudi Arabia.
J Cardiovasc Dev Dis. 2024 Oct 3;11(10):307. doi: 10.3390/jcdd11100307.
Prolonged sitting is a risk factor for cardiovascular disease (CVD). We examined whether moderate aerobic exercise prior to prolonged sitting (EX + SIT) has protective effects on peripheral and central cardiovascular and autonomic measures.
Young women ( = 26; 23.4 ± 4.3 years old; BMI = 23.1 ± 4.3) completed two sessions in random order: (1) EX + SIT, which consisted of 25 min of moderate aerobic exercise followed by a 3 h prolonged sitting bout, and (2) a 3 h prolonged sitting bout only (SIT-only). Seated peripheral and central blood pressure (BP), pulse wave velocity (PWV), and heart rate variability (HRV) were measured at baseline and after 1 h, 2 h, and 3 h of sitting. Generalized linear mixed models with random effects examined the effects of conditions (i.e., EX + SIT vs. SIT) on BP, PWV, and HRV while adjusting for baseline values.
Only peripheral and central diastolic BP (β = 2.18; = 0.016 and β = 1.99; = 0.034, respectively) were significantly lower in the EX + SIT condition compared to the SIT-only condition. No differences were detected in other BP, PWV, or HRV variables between the two conditions ( > 0.05 for all).
Performing moderate aerobic exercise in the morning before engaging in prolonged sitting bouts may reduce some of the prolonged-sitting-induced cardiovascular impairments in young women. Further research is needed to confirm these findings in males and middle-aged/older adults.
长时间坐着是心血管疾病（CVD）的一个风险因素。我们研究了在长时间坐着之前进行适度有氧运动（EX + SIT）是否对外周和中枢心血管及自主神经指标具有保护作用。
年轻女性（n = 26；23.4±4.3岁；BMI = 23.1±4.3）以随机顺序完成两个阶段：（1）EX + SIT，包括25分钟的适度有氧运动，然后是3小时的长时间坐着，以及（2）仅3小时的长时间坐着（仅SIT）。在基线以及坐着1小时、2小时和3小时后测量坐位外周和中心血压（BP）、脉搏波速度（PWV）和心率变异性（HRV）。具有随机效应的广义线性混合模型在调整基线值的同时检查条件（即EX + SIT与SIT）对BP、PWV和HRV的影响。
与仅SIT条件相比，EX + SIT条件下仅外周和中心舒张压（β = 2.18；P = 0.016和β = 1.99；P = 0.034）显著更低。在两种条件之间的其他BP、PWV或HRV变量中未检测到差异（所有P>0.05）。
在长时间坐着之前的早晨进行适度有氧运动可能会减少年轻女性中一些由长时间坐着引起的心血管损伤。需要进一步研究以在男性和中年/老年人中证实这些发现。
