Rheumatology Department, Hospital l'Archet 1, 242 Route de Saint Antoine de Ginestiere, 06200 Nice, France.
J Rheumatol. 2011 Jun;38(6):1009-11. doi: 10.3899/jrheum.100828. Epub 2011 Mar 16.
To compare etanercept (anti-tumor necrosis factor-α) with intraarticular (IA) corticosteroid injections to treat rheumatoid arthritis (RA).
Patients with RA who had persistent monoarthritis received etanercept or IA corticosteroid injections. Efficacy was compared at Weeks 4 and 24.
Thirty-four patients were included (8 dropped out). Mean age was 58.8 years. No difference between groups was found at Weeks 4 or 24, but both groups showed significant improvement at Weeks 4 and 24 compared to baseline.
Etanercept and IA steroid injections resulted in significant improvement at Week 4 that persisted to Week 24. There was no significant difference in outcome between the groups.
比较依那西普（抗肿瘤坏死因子-α）与关节内（IA）皮质类固醇注射治疗类风湿关节炎（RA）的效果。
患有持续性单关节炎的 RA 患者接受依那西普或 IA 皮质类固醇注射治疗。在第 4 周和第 24 周比较疗效。
34 例患者入选（8 例脱落）。平均年龄为 58.8 岁。第 4 周和第 24 周时两组间无差异，但与基线相比，两组在第 4 周和第 24 周均有显著改善。
依那西普和 IA 类固醇注射在第 4 周时显著改善，并持续至第 24 周。两组的结果无显著差异。
