Lauriello G, Giella D, Berra A, Matonti V
I Divisione di Pneumotisiologia, USL N. 53, Presidio Ospedaliero G. da Procida, Salerno.
Clin Ter. 1990 Apr 30;133(2):87-90.
The authors treated 34 patients with acute bronchopulmonary disease or flare-ups of chronic ones with equal doses of ambroxol and ceftriaxone considering the homogeneity of the morbid processes. Patients were divided into two groups of 17 subjects each: group A was given a polyvalent oral bacterial vaccine, group B a placebo. Relevant differences were found between the experimental and control groups concerning cough (score: A = 108, B = 119), duration of expectoration (A = 5.3 days, B = 6.4 days), duration of antibiotic therapy (A = 8.0 days, B = 8.8 days), and length of hospitalization (A = 10.9 days, B = 12.0 days). Differences were slight as far as duration of fever, characteristics of cough and objective findings on the chest were concerned.
考虑到发病过程的同质性,作者用等量的氨溴索和头孢曲松治疗了34例急性支气管肺部疾病患者或慢性疾病急性发作患者。患者被分为两组,每组17人:A组给予多价口服细菌疫苗,B组给予安慰剂。在咳嗽(评分:A组=108,B组=119)、咳痰持续时间(A组=5.3天,B组=6.4天)、抗生素治疗持续时间(A组=8.0天,B组=8.8天)和住院时间(A组=10.9天,B组=12.0天)方面,实验组和对照组之间存在相关差异。就发热持续时间、咳嗽特征和胸部客观检查结果而言,差异较小。